利用进化聚类技术在逆转录病毒蛋白质组序列中发现生物电子学相关性

R. Garza-Domínguez, E. Bautista-Thompson
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引用次数: 1

摘要

本文描述了一组逆转录病毒蛋白质组序列的聚类分析。从序列中计算出赖氨酸-精氨酸浓度向量,并对其进行分析,以确定物种之间的相关性。计算策略是基于K-Means算法将数据划分为不相交的点集。为了优化聚类结构,引入了基于进化规划的搜索方法。实验结果显示了许多有趣和意想不到的相似之处。在电子迁移理论的背景下,这些相似性可能暗示了生物电子学的关系。
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Finding Bioelectronics Correlations in Retro-transcribing Viral Proteomic Sequences Using an Evolutionary Clustering Technique
A cluster analysis on a set of Retro-Transcribing viral proteomic sequences is described in this paper. A Lysine-Arginine concentration vector is calculated from the sequences and analyzed to identify correlations among species. The computational strategy is based on the K-Means algorithm to partition the data into disjoint sets of points. A search method based on Evolutionary Programming is incorporated, in order to optimize the cluster structures. Experimental results show a number of interesting and unexpected similarities. These similarities could suggest bioelectronics relationships, in the context of the electronic mobility theory.
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