蛋白质分类的贝叶斯方法

L. Merschmann, A. Plastino
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引用次数: 5

摘要

在这项工作中,我们提出了一种基于贝叶斯分类器的蛋白质分类新方法。我们的目标是根据它们的基序组成来预测新的蛋白质序列的功能家族。为此,从Prosite(一个精心策划的蛋白质家族数据库)中提取的数据集被用作训练数据集。在进行的实验中,将我们的分类器的性能与其他已知的数据挖掘方法进行了比较。计算结果表明,所提出的方法优于其他方法,并且对于具有类似问题特征的问题看起来非常有希望。
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A Bayesian approach for protein classification
In this work, we propose a new approach for protein classification based on Bayesian classifiers. Our goal is to predict the functional family of novel protein sequences based on their motif composition. For this purpose, datasets extracted from Prosite, a curated protein family database, are used as training datasets. In the conducted experiments, the performance of our classifier is compared to other known data mining approaches. The computational results have shown that the proposed method outperforms the other ones and looks very promising for problems with characteristics similar to the problem addressed here.
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