早期呼吸暂停测试对器官捐献有影响吗?

Ayşe Güsün Halitoğlu, Mukaddes Saba Saygılı, A. Kaya, M. Tercan
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引用次数: 1

摘要

目的:本研究旨在确定2006-2017年健康科学大学Şanlıurfa Mehmet Akif İnan培训与研究医院的呼吸暂停测试时间对脑死亡(BD)患者器官捐赠的影响程度。材料与方法:回顾性分析2006-2017年间诊断为BD的105例患者。由于样本仅限于全国人口,13例叙利亚病例被排除在研究之外。记录病例的人口学特征、临床诊断、重症监护住院至呼吸暂停测试的间隔时间、呼吸暂停测试至心脏循环骤停的间隔时间、呼吸暂停测试至BD委员会决定时间的间隔时间、首次就诊时格拉斯哥昏迷评分、APACHE II评分。结果:本组92例患者中,女性33例(35.9%),男性59例(64.1%)。重症监护病房入院时最常见的诊断是外伤,占52.2% (n=48),其余分别为中风(35.9%)(n=33)、心肺复苏后缺氧脑损伤(6.5%)(n=6)和窒息(5.4%)(n=5)。在被诊断为双相障碍的患者中,12%的家庭接受了器官捐赠。接受器官捐献的;从首次入住重症监护病房到呼吸暂停试验阳性的中位数时间为57小时,而器官捐献被拒绝的中位数时间为86.8小时(p>0.05)。结论:我院BD患者逐年增加,但器官捐献率与西部地区相比仍显不足。
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Does Early Apnea Test Have an Effect on the Organ Donation?
Objective: This study aims to determine the extent to which the timing of apnea test has influence on the organ donation of those patients diagnosed with the brain death (BD) at University of Health Sciences, Şanlıurfa Mehmet Akif İnan Training and Research Hospital between the years of 2006-2017. Materials and Methods: One hundred and five patients diagnosed with BD between the years of 2006-2017 were analyzed retrospectively. Since the sample is limited to the national population, 13 Syrian cases are excluded from the study. The demographic characteristics of the cases, their clinical diagnoses, elapsed time between intensive care hospitalization and apnea test, duration between apnea test and cardio-circulatory arrest, elapsed time between apnea test and BD council decision time, Glasgow coma scores at first visit, APACHE II scores were recorded. Results: Of the ninety two cases evaluated in the study, 33 (35.9%) were female and 59 (64.1%) were male. While the most frequent diagnosis during the admission to the intensive care unit was trauma with 52.2% (n=48), the rest was found as stroke with 35.9% (n=33), anoxic brain injury after cardiopulmonary resuscitation with 6.5% (n=6), and asphyxia with 5.4% (n=5) respectively. Among the patients who have been diagnosed with BD, 12% of the family accepted organ donation. In the cases who accept organ donation; the median time from the first hospitalization in the intensive care unit to the time that the apnea test was positive is 57 hours whereas the median time is 86.8 hours when the organ donation is rejected (p>0.05). Conclusion: Whereas the number of patients diagnosed with BD in our hospital increases over the years, the organ donation rate is insufficient compared to the western part of the country.
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