会阴固定临时尿道支架治疗后尿道狭窄(初步结果)

P. Kyzlasov, A. Mustafaev, D. Ostrovsky, A. Martov
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Ten patients had stenosis of the urethrocystoneoanastomosis after radical prostatectomy, 6 patients had iatrogenic stenosis of the prostatic urethra, 1 patient had post-radiation stenosis of the bulbo-membranous urethra. All patients in the preoperative and postoperative periods underwent: IPSS-QoL questioning, uroflowmetry, bladder ultrasound with residual urine volume evaluation, urethroscopy, ascending and micturition urethrocystography. The first stage was an internal optical urethrotomy according to the standard technique. Then, a urethral stent was installed in the area of dissected stenosis. The second stage was an incision in the perineum, the urethra was isolated, and under optical control, through the perineum, the stent was fixed to the urethra with non-absorbable suture material. The stent was removed endoscopically after 6 months.Results. The median surgery duration averaged 45 minutes. Patients were discharged 2 to 3 days after surgery. 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摘要

介绍。尿道成形术是治疗尿道狭窄的“金标准”。然而,通常与老年和老年有关,以及由于存在伴随疾病,由于其一定的侵入性,不可能进行尿道成形术。在这种情况下,治疗方法之一是安装尿道支架。但由于支架移位频繁,结皮频率高,该方法尚未得到实际应用。我们开发的方法避免了支架的迁移。研究目的:目的:评价经会阴固定尿道支架的即刻效果。材料和方法。2019年2月以来,共收治18例68 ~ 84岁尿道狭窄患者。根治性前列腺切除术后尿道结石吻合口狭窄10例,医源性前列腺尿道狭窄6例,放射后球膜性尿道狭窄1例。所有患者术前、术后均行:IPSS-QoL询问、尿流量测定、膀胱超声伴残尿量评估、尿道镜检查、升尿尿尿道造影术。第一阶段是按照标准技术进行内光学尿道切开术。然后在解剖狭窄区放置尿道支架。第二阶段为会阴切口,隔离尿道,在光学控制下,通过会阴,用不可吸收的缝合材料将支架固定在尿道上。6个月后,内镜下取出支架。平均手术时间为45分钟。术后2 ~ 3天出院。最长观察期为20个月。观察期间未发生一例支架移位。所有患者均表现为Qmax持续升高,无尿残。应激性尿失禁6例,完全性尿失禁4例。支架取出后6个月对照尿道镜检查,所有患者均发现临床上不明显的尿道狭窄。在所有病例中,均发现中度支架结痂迹象。5例患者出现排尿困难现象,经直肠栓剂加非甾体抗炎药停用,同时服用消毒药。IPPS-QoL问卷的数据证实了治疗的积极效果。临时放置尿道支架治疗尿道狭窄是一种有效的微创治疗方法。通过会阴的固定技术可以防止所有病例的移位。这种治疗方法显著提高了因某种原因禁忌行尿道成形术患者的生活质量。然而,这项技术需要更长的观察和分析时间。
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Temporary urethral stent with perineal fixation for posterior urethral stenosis (preliminary results)
Introduction. Urethroplasty is the “gold standard” treatment of urethral stenosis. However, often in connection with old and senile age, as well as due to the presence of concomitant diseases, it is not possible to carry out urethroplasty due to its certain invasiveness. In such cases, one of the methods of treatment is the installation of a urethral stent. But this method has not found practical application due to the frequent migration of stent and the high frequency of its incrustation. The approach developed by us avoids stent migration.Purpose of the study. To evaluate the immediate results of the placement of a urethral stent with fixation through the perineum.Materials and methods. A total of 18 patients with urethral stenosis aged 68 to 84 years have been operated on since February 2019. Ten patients had stenosis of the urethrocystoneoanastomosis after radical prostatectomy, 6 patients had iatrogenic stenosis of the prostatic urethra, 1 patient had post-radiation stenosis of the bulbo-membranous urethra. All patients in the preoperative and postoperative periods underwent: IPSS-QoL questioning, uroflowmetry, bladder ultrasound with residual urine volume evaluation, urethroscopy, ascending and micturition urethrocystography. The first stage was an internal optical urethrotomy according to the standard technique. Then, a urethral stent was installed in the area of dissected stenosis. The second stage was an incision in the perineum, the urethra was isolated, and under optical control, through the perineum, the stent was fixed to the urethra with non-absorbable suture material. The stent was removed endoscopically after 6 months.Results. The median surgery duration averaged 45 minutes. Patients were discharged 2 to 3 days after surgery. The maximum observation period was 20 months. During the observation period, not a single case of stent migration was recorded. All patients showed a persistent increase in Qmax and no residual urine. Six patients had a stress component of urinary incontinence, 4 patients had total urinary incontinence. According to control urethrocystoscopy 6 months after stent removal, clinically insignificant urethral stenosis was noted in all patients. In all cases, moderate signs of stent encrustation were identified. Dysuric phenomena disturbed 5 patients, who were stopped by rectal suppositories with NSAIDs, as well as taking herbal uroseptics. The data from the IPPS-QoL questionnaires confirm the positive effect of the treatment.Conclusions. Temporary placement of a urethral stent for urethral stenosis is an effective minimally invasive treatment. The technique of fixation through the perineum allows preventing migration in all cases. This approach to treatment significantly improves the quality of life of patients who were contraindicated for urethroplasty for one reason or another. However, the technique requires longer observation and analysis.
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