新发现的细胞形状促进蛋白复合物参与维持幽门螺杆菌独特的螺旋形状

F. Paczkowski
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引用次数: 0

摘要

幽门螺杆菌(h.p ylori)独特的螺旋形状有助于这种生物在其目标宿主的消化器官中定植。已经发现,幽门螺杆菌螺旋细胞形状形成的关键决定因素是Csd5蛋白,它参与多种细胞形状,促进与细胞壁和其他各种蛋白质的相互作用。这一发现具有重要的临床意义,因为它概述了Csd5作为未来治疗幽门螺杆菌感染的潜在药物靶点。
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Newly Discovered Cell Shape Promoting Protein Complex Involved in the Maintenance of Distinct Helical Shape of Helicobacter Pylori
The distinct helical shape of the bacterium Helicobacter Pylori (H. pylori) assists this organism in colonizing the digestive organs of its target host. It has been discovered that a key determinant of helical cell shape formation in H. pylori is the Csd5 protein, which engages in multiple cell shape promoting interactions with the cell wall and other various proteins. This finding has significant clinical implications, as it outlines Csd5 as a potential drug target for treating H. pylori infection in the future.
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