维生素D与口腔扁平地衣的关系。探索性系统综述

M. Astorga, G. Fuentes, R. Quitral, K. Cordero
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摘要

摘要:探讨维生素D (VD)在口腔扁平苔藓(OLP)发生发展及治疗中的作用。探索性系统评价于2021年4月使用Pubmed / Medline、Ebsco和Scopus / Elsevier数据库进行。术语“口腔扁平苔藓”和“维生素研究的不足程度描述。最后,鉴于VD在免疫过程中的作用以及使用VD改善OLP症状的报告,补充VD作为佐剂作为减轻症状的替代方案出现。与健康患者相比,诊断为OLP的患者血清VD水平不足。微量营养素缺乏与过度的炎症反应和免疫系统的改变有关。在严重的OLP患者中,VD补充作为皮质类固醇治疗的辅助是有益的。然而,有限的证据使得有必要进行更多的临床研究来重申VD作为OLP补充治疗的有效性。
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Relación entre la Vitamina D y el Liquen Plano Oral. Revisión Sistemática Exploratoria
˚ ABSTRACT: To determine the role of vitamin D (VD) in the development and treatment of oral lichen planus (OLP). An exploratory systematic review was carried out during April of 2021 using the databases Pubmed / Medline, Ebsco and Scopus / Elsevier. The terms "Oral lichen planus" and "Vitamin studies magnitude of the deficit is described. Finally, supplementation with VD as an adjuvant arises as an alternative for the reduction of symptoms, given the role of VD in immune processes and reports of improvements in OLP symptoms with its use. Patients diagnosed with OLP have insufficient levels of serum VD compared to healthy patients. Micronutrient deficiency is related to an exaggerated inflammatory response and alterations in the immune system. VD supplementation in patients with OLP would be beneficial as an adjunct to corticosteroid treatment in severe cases. However, the limited evidence makes it necessary to carry out more clinical studies to reaffirm the effectiveness of VD as a complementary treatment for OLP.
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