功能生物医学用蛋壳羟基磷灰石粉体的合成与表征

E. Buluş, Deniz Ismık, D. S. Mansuroğlu, Y. Sahin, G. Tosun
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摘要

磷灰石磷酸盐被认为属于生物陶瓷的范畴。透明质酸及其衍生物被用于医学、骨科和牙科领域,以支持新骨细胞的生长。透明质酸结构具有较高的生物相容性,在生物医学领域有着广泛的应用。另一方面,HA结构的合成需要复杂的技术(微波烧结、水热合成等),生产成本高。本研究旨在利用天然材料制备具有良好生物相容性的纳米磷灰石结构。采用简单的热板法从蛋壳中获得天然的纳米级透明质酸。经过不同温度下的煅烧和烧结工艺,用红外光谱(FT-IR)和x射线衍射(XRD)对制备的磷灰质磷酸盐粉体进行了结构表征。形态学研究已进行了FEG-SEM图像。对制备的纳米生物陶瓷进行了生物学研究,结果表明这些纳米材料在组织工程方面具有广阔的应用前景。
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Synthesis and characterization of hydroxyapatite powders from eggshell for functional biomedical application
Apatitic phosphates are considered within the category of bioceramics. HA and its derives are used of in the fields of medicine, orthopedics and dentistry in order to support a grow up of new bone cells. HA structures have a high biocompability and are widely in biomedical applications. On the other hand, synthesis of HA structures necessitates complex technologies (microwave sintering, hydrothermal synthesis etc.) and their production costs high. This study aims the production of nano apatitic structures with great biocompability from a natural material. Simple hotplate method was used to obtain natural, nano scale HA from eggshells. After calcination and sintering processes at different temperatures, the obtained apatitic phosphate powders have been structurally characterized by infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). Morphological investigation has been conducted by FEG-SEM images. Biological investigations have been carried out for the produced nanosized bioceramics and the results reveal that these nanomaterials are promising for tissue engineering purposes.
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