DNA数据存储的纳米孔测序模拟器

Eva Gil San Antonio, T. Heinis, Louis Carteron, Melpomeni Dimopoulou, M. Antonini
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引用次数: 2

摘要

数字数据的指数级增长和当前存储设备的有限容量已经明确需要探索新的存储解决方案。由于其生物学特性,DNA已被证明是这项任务的潜在候选者,它允许以高密度存储信息数百年甚至数千年。随着纳米孔测序技术的发布,DNA数据存储离成为现实又近了一步。许多工作已经提出了模拟这一测序步骤的解决方案,旨在简化处理纳米孔测序读取的算法的开发。然而,这些模拟器的目标是全基因组测序,其特征不同于合成DNA。这项工作提出了一个纳米孔测序模拟器针对DNA数据存储的背景下合成DNA。
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Nanopore Sequencing Simulator for DNA Data Storage
The exponential increase of digital data and the limited capacity of current storage devices have made clear the need for exploring new storage solutions. Thanks to its biological properties, DNA has proven to be a potential candidate for this task, allowing the storage of information at a high density for hundreds or even thousands of years. With the release of nanopore sequencing technologies, DNA data storage is one step closer to become a reality. Many works have proposed solutions for the simulation of this sequencing step, aiming to ease the development of algorithms addressing nanopore-sequenced reads. However, these simulators target the sequencing of complete genomes, whose characteristics differ from the ones of synthetic DNA. This work presents a nanopore sequencing simulator targeting synthetic DNA on the context of DNA data storage.
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