连续流动腹膜透析方案:国营三级保健中心的经验

C. Sreedhara, L. Umesh, N. Raghavendra, V. Leelavathi, Shivaprasad
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背景:慢性动态腹膜透析(CAPD)是印度终末期肾衰竭患者的一种肾脏替代疗法,而不是血液透析。由于其成本和技术要求,在印度主要用于城市地区。本文的目的是报告CAPD作为一种肾脏替代治疗方式的经验,来自印度南部低社会经济人群的一家三级医院。方法。我们报告了一项在南印度一家大型三级医院进行的前瞻性研究。本研究纳入2011年4月至2016年1月间开始接受CAPD治疗的患者,存活和/或接受CAPD治疗随访超过6个月,最后一次随访至2016年7月30日,研究感染率及其可能影响因素。结果。共纳入45例患者。男性24人,女性21人。平均年龄为46±10岁(范围5-70岁),试验结束时平均透析时间为23个月。13.3%的患者转向血液透析(n=6)。1例发生出口感染,6例发生腹膜炎,4例导致导管拔除。另外2例因移位而拔除导管,其中1例再次插入。16名患者在研究中死亡。死亡的主要原因是心血管并发症。腹膜炎发生率为1 / 32个月,优于指南。结论。慢性非卧床腹膜透析(CAPD)是低社会经济人群一种安全可行的肾替代方式。中国的腹膜炎发病率和病因与发达国家相似。它可以作为程序居住在低社会经济群体的ESRD患者在发展中国家,如印度。
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Continuous Ambulatory Peritoneal Dialysis Programme:Experience of State Run Tertiary Care Centre
Background : Chronic ambulatory peritoneal dialysis (CAPD) is a form of renal replacement therapy in patients with end-stage renal failure in India, other than hemodialysis. Because of its cost and technical demand was mostly used in urban area in India. The objective of this paper is to report the experience with CAPD as a modality of renal replacement therapy from a tertiary care hospital in south India with low socioeconomic group of population. Methods.: We report a prospective study in a large south indian tertiary hospital. This study involved the patients who were initiated on CAPD between april 2011 and january 2016 and who survived and/or had more than 6 months follow up on this treatment with last follow up till July 30, 2016 Infection rates as well as factors that may influence them were studied. Results.: Forty five patients were enrolled. There were 24 males and 21 females. The mean age was 46±10 (range 5-70) years and mean duration on dialysis at the end of the trial period was 23 months. Shift to haemodialysis occurred in 13.3% of patients ( n=6). One patient had exit-site infection, six patients had peritonitis and 4 lead to removal of catheter. Other 2 cases catheter removal done for migration and in that one underwent reinsertion.16 patients died in the study. The main cause of death was cardiovascular complications. Peritonitis rate is 1 in 32 patient months, which is better than the guidelines. Conclusion.: Chronic ambulatory peritoneal dialysis (CAPD) is a safe and viable mode of renal replacement in low socioeconomic group of population. The peritonitis rate and aetiology are similar to the developed world. It can use as procedure for ESRD patients dwelling in low socioeconomic group of population in developing countries such as India.
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