自闭症谱系障碍的胃肠道症状

Jenna Logan Schuppener, J. Elder
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引用次数: 1

摘要

本研究的目的是描述自闭症谱系障碍(ASD)患者的特征,以确定临床有用的方法来评估胃肠道(GI)症状,这是一个更大的ASD研究的一部分。从不同的社区机构招募了33名儿童(3-16岁)。使用自闭症诊断观察表(ADOS)筛选潜在的参与者。所有参与者都获得了家长的知情同意,适当时也获得了儿童的同意。家长完成胃肠症状评定量表、布里斯托大便量表(BSC)和社会人口统计表格。在33名参与者中,有14人目前出现胃肠道症状,排便异常。7例有胃肠道症状和排便异常史;两对父母不确定他们的肠胃健康状况。根据BSC评分,13名参与者报告大便坚硬,14名大便正常,6名大便稀。在许多胃肠道症状之间发现中度相关性(r33= .396 - .751),表明这些症状可以聚类以创建一个概况。这些发现具有重要的临床意义,因为ASD的胃肠道症状由于交流和社交障碍而难以诊断,并且可能未得到诊断和治疗。由于护士经常在ASD人群的第一线进行干预,因此进一步表征该人群的胃肠道症状对护士研究人员来说是一个合乎逻辑的角色。
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Gastrointestinal Symptoms in Autism Spectrum Disorders
The purpose of this study was to characterize individuals with autism spectrum disorders (ASD), who are part of a larger ASD study, in order to determine clinically useful ways to evaluate gastrointestinal (GI) symptomology. Thirty-three children (ages 3-16) were recruited from a variety of community agencies. Potential participants were screened using the Autism Diagnostic Observation Schedule (ADOS). Parental informed consent was obtained from all participants and child assent when appropriate. Parents completed the Gastrointestinal Symptom Rating Scale, Bristol Stool Chart (BSC), and sociodemographic form. Of the 33 participants, 14 were currently experiencing gastrointestinal symptoms and had abnormal bowel movements. Seven had a history of gastrointestinal symptoms and abnormal bowel movements; two parents were unsure of their gastrointestinal health. According to the BSC rescore, 13 participants reported hard stools, 14 had normal stools, and six had loose stools. Moderate correlations were found among many GI symptoms (r33= .396 - .751) indicating that these could be clustered to create a profile. These findings are clinically significant because GI symptoms in ASD are difficult to diagnose due to communication and social impairments and may go undiagnosed and untreated.  Further characterizing GI symptomology in this population is a logical role for nurse researchers since nurses are often on the front line intervening within the ASD population.  
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