数量

B. Gillham
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引用次数: 345

摘要

CNVs是结构性遗传变异。它们的检测目前是生物信息学领域中一个被广泛讨论的问题,部分原因是它们被证明与癌症、艾滋病和神经精神疾病等疾病有(或正或负)联系。在本文中,我们将研究几种方法及其适用性,以便深入了解所提出的挑战以及如何面对这些挑战。
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CNVs are structural genetic variations. Their detection is currently a heavily discussed problem in the area of bioinformatics, in part due to their proved (positive or negative) association with diseases like cancer, AIDS and neuropsychiatric disorders. In this text, we will study several approaches and their applicability, in order to obtain an insight into the challenges presented and how they are confronted.
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