环孢素导致牙龈增大:一例报告

Andrés Campolo González , Lorena Núñez Castañeda , Pablo Romero Romano , Andrés Rodríguez Schneider , María de los Ángeles Fernández Toro , Francisca Donoso Hofer
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引用次数: 6

摘要

牙龈肿大是指牙龈体积异常增大,引起美容改变和临床症状,如牙龈出血、牙周疾病、病理性牙齿移位等。这种情况可能是某些药物的副作用,如抗惊厥药、钙通道阻滞剂和免疫抑制剂。一位74岁男性患者,既往有慢性肾功能衰竭肾移植病史,接受环孢素治疗14年,主诉为牙龈肿大。治疗的基础是拔牙、活组织检查和牙周治疗。两个月后观察到病变完全消退。目前治疗这种疾病的方法主要集中在斑块控制上。应采用多学科方法,并制定临床方案,以便及早治疗和避免更严重的疾病表现。
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Agrandamiento gingival por ciclosporina: reporte de un caso

Gingival enlargement is an abnormal increased volume of the gum that induces cosmetic changes and clinical symptoms, such as gingival bleeding, periodontal disorders, pathological tooth migration, among others. This condition can be a side effect of certain drugs such as anticonvulsants, calcium channel blockers, and immunosuppressants. A 74 year-old male patient with a medical record of kidney transplant secondary to chronic renal failure receiving cyclosporine for the past 14 years is referred to our Hospital with the chief complaint of gingival enlargement. The treatment is based on tooth extractions, biopsy and periodontal treatment. A complete regression of the lesion was observed after two months. The current approach to treat this disease is focused on plaque control. A multidisciplinary approach should be used and clinical protocols prepared that allow early treatment and avoidance of more aggressive disease expression.

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