宫颈癌患者近距离放疗计划及膀胱直肠剂量测定的线性关系

S. D. Astuti, Gege Ayu Listya, N. Fitriyah, B. Suhartono
{"title":"宫颈癌患者近距离放疗计划及膀胱直肠剂量测定的线性关系","authors":"S. D. Astuti, Gege Ayu Listya, N. Fitriyah, B. Suhartono","doi":"10.1109/ISSIMM.2018.8727731","DOIUrl":null,"url":null,"abstract":"Cervical cancer was one of the most dangerous cancer suffered by women all over the world. One treatment method for cervical cancer was using radiotherapy. Cervical cancer can be treated using 2 types of radiotherapy such as brachytherapy and linac. The organ at Risk (OAR) were healthy organs which the most adjacent to the cervix namely bladder and rectum. The total dose received by OAR must be below dose tolerance. The purpose of this study was to determine the total dose received by bladder and rectum from a combination of brachytherapy and linac treatment (B-L) compared with combination linac and linac treatment (L-L). Prescribe dose for booster brachytherapy was 3x7 Gy and for booster, linac was 10x2 Gy. Evaluating the dose was by analyzing Dose Volume Histogram (DVH) bladder and rectum in 2cc volume (D2cc). The average total dose received by bladder from B-L was ($66.44\\pm 0.05$) Gy and from L-L was ($66.55\\pm 0.02$) Gy; the average total dose received by rectum from B-L was ($66.02\\pm 0.05$) Gy and from L-L was ($67.45\\pm 0.02$) Gy) respectively. Statistical analysis was carried out by Independent T-test, it is convinced that there was no significant difference ($\\mathbf{p} > 0.05$) in total dose received by bladder from both B-L and L-L treatment, while there was a significant difference ($\\mathbf{p} < 0.05$) in total dose received by rectum from both treatments. The total dose received by bladder and rectum from both B-L and L-L treatment remained in safety zone as those were still below the dose tolerance based on GEC-ESTRO recommendations (D2cc bladder<90 Gy and D2cc rectum<75 Gy).","PeriodicalId":178365,"journal":{"name":"2018 3rd International Seminar on Sensors, Instrumentation, Measurement and Metrology (ISSIMM)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Brachytherapy Treatment Planning and Linac for Dose Measurement of Bladder and Rectum in Cervical Cancer Patients\",\"authors\":\"S. D. Astuti, Gege Ayu Listya, N. Fitriyah, B. Suhartono\",\"doi\":\"10.1109/ISSIMM.2018.8727731\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cervical cancer was one of the most dangerous cancer suffered by women all over the world. One treatment method for cervical cancer was using radiotherapy. Cervical cancer can be treated using 2 types of radiotherapy such as brachytherapy and linac. The organ at Risk (OAR) were healthy organs which the most adjacent to the cervix namely bladder and rectum. The total dose received by OAR must be below dose tolerance. The purpose of this study was to determine the total dose received by bladder and rectum from a combination of brachytherapy and linac treatment (B-L) compared with combination linac and linac treatment (L-L). Prescribe dose for booster brachytherapy was 3x7 Gy and for booster, linac was 10x2 Gy. Evaluating the dose was by analyzing Dose Volume Histogram (DVH) bladder and rectum in 2cc volume (D2cc). The average total dose received by bladder from B-L was ($66.44\\\\pm 0.05$) Gy and from L-L was ($66.55\\\\pm 0.02$) Gy; the average total dose received by rectum from B-L was ($66.02\\\\pm 0.05$) Gy and from L-L was ($67.45\\\\pm 0.02$) Gy) respectively. Statistical analysis was carried out by Independent T-test, it is convinced that there was no significant difference ($\\\\mathbf{p} > 0.05$) in total dose received by bladder from both B-L and L-L treatment, while there was a significant difference ($\\\\mathbf{p} < 0.05$) in total dose received by rectum from both treatments. The total dose received by bladder and rectum from both B-L and L-L treatment remained in safety zone as those were still below the dose tolerance based on GEC-ESTRO recommendations (D2cc bladder<90 Gy and D2cc rectum<75 Gy).\",\"PeriodicalId\":178365,\"journal\":{\"name\":\"2018 3rd International Seminar on Sensors, Instrumentation, Measurement and Metrology (ISSIMM)\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 3rd International Seminar on Sensors, Instrumentation, Measurement and Metrology (ISSIMM)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ISSIMM.2018.8727731\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 3rd International Seminar on Sensors, Instrumentation, Measurement and Metrology (ISSIMM)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISSIMM.2018.8727731","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

摘要

子宫颈癌是全世界妇女患的最危险的癌症之一。宫颈癌的一种治疗方法是放疗。宫颈癌可采用近距离放射治疗和直线放射治疗两种类型的放射治疗。危险器官(OAR)为与子宫颈最邻近的健康器官,即膀胱和直肠。OAR接受的总剂量必须低于剂量耐受。本研究的目的是确定近距离放射治疗和直线治疗联合(B-L)与直线治疗和直线治疗联合(L-L)对膀胱和直肠的总剂量。近距离强化治疗处方剂量为3x7 Gy,强化治疗处方剂量为10x2 Gy。通过分析膀胱和直肠2cc体积(D2cc)的剂量-体积直方图(DVH)来评估剂量。B-L的膀胱平均总剂量为($66.44\pm 0.05$) Gy, L-L的膀胱平均总剂量为($66.55\pm 0.02$) Gy;B-L和L-L的直肠平均总剂量分别为($66.02\pm 0.05$) Gy和($67.45\pm 0.02$) Gy。采用独立t检验进行统计分析,认为B-L和L-L两种治疗方式膀胱总剂量差异无统计学意义($\mathbf{p} > 0.05$),直肠总剂量差异有统计学意义($\mathbf{p} < 0.05$)。膀胱和直肠接受B-L和L-L治疗的总剂量仍然在安全范围内,因为它们仍然低于基于GEC-ESTRO推荐的耐受剂量(D2cc膀胱<90 Gy, D2cc直肠<75 Gy)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Brachytherapy Treatment Planning and Linac for Dose Measurement of Bladder and Rectum in Cervical Cancer Patients
Cervical cancer was one of the most dangerous cancer suffered by women all over the world. One treatment method for cervical cancer was using radiotherapy. Cervical cancer can be treated using 2 types of radiotherapy such as brachytherapy and linac. The organ at Risk (OAR) were healthy organs which the most adjacent to the cervix namely bladder and rectum. The total dose received by OAR must be below dose tolerance. The purpose of this study was to determine the total dose received by bladder and rectum from a combination of brachytherapy and linac treatment (B-L) compared with combination linac and linac treatment (L-L). Prescribe dose for booster brachytherapy was 3x7 Gy and for booster, linac was 10x2 Gy. Evaluating the dose was by analyzing Dose Volume Histogram (DVH) bladder and rectum in 2cc volume (D2cc). The average total dose received by bladder from B-L was ($66.44\pm 0.05$) Gy and from L-L was ($66.55\pm 0.02$) Gy; the average total dose received by rectum from B-L was ($66.02\pm 0.05$) Gy and from L-L was ($67.45\pm 0.02$) Gy) respectively. Statistical analysis was carried out by Independent T-test, it is convinced that there was no significant difference ($\mathbf{p} > 0.05$) in total dose received by bladder from both B-L and L-L treatment, while there was a significant difference ($\mathbf{p} < 0.05$) in total dose received by rectum from both treatments. The total dose received by bladder and rectum from both B-L and L-L treatment remained in safety zone as those were still below the dose tolerance based on GEC-ESTRO recommendations (D2cc bladder<90 Gy and D2cc rectum<75 Gy).
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Design and Manufacturing of Motor-Tendon Actuator for a Soft Starfish-Like Robot Gray Scale and Edge Detecting Method To Extract Raw Data in The Diffusivity Measurement System Omnidirectional Sensing for Escaping Local Minimum on Potential Field Mobile Robot Path Planning in Corridors Environment Enhancing Temperature Sensitivity for The SMS Fiber Structure Temperature Sensor Copyright
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1