中东地区SARS-CoV-2基本复制数初步估计

ISSUE TEN Pub Date : 2020-05-01 DOI:10.2471/blt.20.262295
B. Rahman, Imad A. Aziz, Fuad W. Khdhr, Dler Mahmood
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引用次数: 17

摘要

截至2020年4月9日,中东地区已确诊新冠肺炎感染病例142490例,其中5705例死亡。卡塔尔、巴林、伊拉克、科威特、阿联酋、阿曼、黎巴嫩、沙特阿拉伯等大部分国家都从伊朗输入了新冠肺炎病例。利用世卫组织网页上的现有数据,我们追踪了截至2020年4月9日的流行曲线,并通过中东国家的易感-感染-恢复(SIR)模型估计了COVID-19的基本繁殖数。中东国家和地区的流行曲线显示出与伊朗相似的趋势,只是时间延迟了几周。在SIR模型中,土耳其的基本繁殖数为7.41,阿曼最低为2.60,而伊朗、科威特、巴林、卡塔尔、沙特阿拉伯、阿拉伯联合酋长国、阿曼、约旦、埃及、黎巴嫩、叙利亚、以色列、西岸和加沙地带领土以及塞浦路斯的基本繁殖数分别为4.13、2.71、3.39、4.18、4.45、2.75、2.60、3.52、3.35、3.16、4.99、4.08、2.89和4.05。该研究表明,根据中东国家的估计,2019冠状病毒病(COVID-19)有早期爆发的重要趋势,平均为3.76,中东国家的中位数和四分位数范围(IQR)均为3.76。
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Preliminary Estimation of the Basic Reproduction Number of SARS-CoV-2 in the Middle East
Up to April 9, 2020, 142490 cases have been confirmed as COVID-19 infection including 5705 associated deaths in the Middle East. Most of the countries, such as Qatar, Bahrain, Iraq, Kuwait, United Arab Emirates (UAE), Oman, Lebanon, and Saudi Arabia have imported COVID-19 cases from Iran. Using the available data from WHO webpage, up to 9 April 2020, we traced epidemic curves and estimated the basic reproduction number ( ) of COVID-19 through the susceptible-infectious-recovered (SIR) model for the Middle East countries. Epidemic curves for Middle East countries and territory show similar trend as Iran, with a couple of weeks’ delay in time. In SIR model, ranged between 7.41 as in Turkey to lowest as 2.60 for Oman whereas basic reproduction number for Iran, Kuwait, Bahrain, Qatar, Saudi Arabia, United Arab Emirates (UAE), Oman, Jordan, Egypt, Lebanon, Syria, Israel, West Bank and Gaza Strip territory, and Cyprus were 4.13, 2.71, 3.39, 4.18, 4.45, 2.75, 2.60, 3.52, 3.35, 3.16, 4.99, 4.08, 2.89, and 4.05, respectively. This study indicates an important trend on an early outbreak of COVID-19 based on estimated for the Middle East countries, mean 3.76 for COVID-19, with median and interquartile range (IQR) in the Middle East.
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