不同种族孕妇维生素D状况及其对不良妊娠和儿童结局的潜在影响

Pardis Keshavarz, Parisa Jandaghi, Mojtaba Shafiee, Naorin Islam, H. Vatanparast
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引用次数: 3

摘要

孕妇孕期维生素D缺乏是一个广泛关注的公共卫生问题。种族和民族分别作为生物和文化因素,可以通过肤色、阳光照射和饮食摄入量的差异来影响维生素D的状态。孕妇维生素D水平低可能对母亲和胎儿都有不利影响。维生素D缺乏和不足与多种不良妊娠结局有关,如妊娠糖尿病、先兆子痫和早产。此外,母亲缺乏维生素D与婴儿和儿童的一些不良健康结果有关。这些例子包括但不限于生长障碍、骨骼问题和自身免疫性疾病,如1型糖尿病和哮喘。本章回顾了不同种族怀孕期间的维生素D状况,研究了不利的怀孕和儿童结局,随后讨论了孕产妇和儿童维生素D状况与成功干预之间的关系。有强有力的证据表明维生素D与怀孕期间的一些健康状况之间存在关联,但需要更多的研究来证实另一种说法。现有的大量证据证明,需要制定精心设计的政策和系统的干预措施,以确保不同民族和种族群体的孕妇及其后代的最佳维生素D水平。
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Maternal Vitamin D Status among Different Ethnic Groups and Its Potential Contribution to Adverse Pregnancy and Child Outcomes
Maternal vitamin D deficiency in pregnancy is a widespread public health concern. Race and ethnicity as biological and cultural factors, respectively, can affect vitamin D status through differences in skin color, sunlight exposure, and dietary intake. Low maternal vitamin D status in pregnancy may affect both mother and fetus adversely. Vitamin D deficiency and insufficiency are linked to a wide variety of adverse pregnancy outcomes such as gestational diabetes, preeclampsia, and preterm delivery. Furthermore, maternal vitamin D deficiency has been linked to several adverse health outcomes in infants and children. The examples include, but not limited to, impaired growth, skeletal problems, and autoimmune diseases such as type 1 diabetes and asthma. This chapter reviews the vitamin D status during pregnancy across different ethnic groups, looking into the adverse pregnancy and child outcomes, followed by a discussion on the association between maternal and child vitamin D status and successful interventions. Strong evidence exists about the association between vitamin D and some health outcomes during pregnancy, while more studies are needed to confirm the other claim. The existing body of evidence justifies the need for well-designed policies and systematic interventions to ensure optimal vitamin D status of pregnant women and their offsprings across different ethnic and racial groups.
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