C. Fuchsberger, H. Hübl, G. Schäfer, A. Pelzer, G. Bartsch, H. Klocker, Nicola Barbarini, R. Bellazzi, W. Wieder, G. Bonn
{"title":"用于组织表征的空间蛋白质组学数据的分析和可视化","authors":"C. Fuchsberger, H. Hübl, G. Schäfer, A. Pelzer, G. Bartsch, H. Klocker, Nicola Barbarini, R. Bellazzi, W. Wieder, G. Bonn","doi":"10.1109/CBMS.2008.119","DOIUrl":null,"url":null,"abstract":"Spatial proteomic profiling of tissue sections provides in situ molecular analysis of proteins and peptides. Analysis and visualization of these high-dimensional data cubes is challenging. We present a methodology for this task based on a novel developed algorithm for the feature identification and reduction step. To show the validity of our approach, we analyzed prostate cancer tissue sections with an adapted kernel-density based clustering algorithm.","PeriodicalId":377855,"journal":{"name":"2008 21st IEEE International Symposium on Computer-Based Medical Systems","volume":"68 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2008-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Analysis and Visualization of Spatial Proteomic Data for Tissue Characterization\",\"authors\":\"C. Fuchsberger, H. Hübl, G. Schäfer, A. Pelzer, G. Bartsch, H. Klocker, Nicola Barbarini, R. Bellazzi, W. Wieder, G. Bonn\",\"doi\":\"10.1109/CBMS.2008.119\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Spatial proteomic profiling of tissue sections provides in situ molecular analysis of proteins and peptides. Analysis and visualization of these high-dimensional data cubes is challenging. We present a methodology for this task based on a novel developed algorithm for the feature identification and reduction step. To show the validity of our approach, we analyzed prostate cancer tissue sections with an adapted kernel-density based clustering algorithm.\",\"PeriodicalId\":377855,\"journal\":{\"name\":\"2008 21st IEEE International Symposium on Computer-Based Medical Systems\",\"volume\":\"68 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-06-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2008 21st IEEE International Symposium on Computer-Based Medical Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CBMS.2008.119\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2008 21st IEEE International Symposium on Computer-Based Medical Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CBMS.2008.119","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Analysis and Visualization of Spatial Proteomic Data for Tissue Characterization
Spatial proteomic profiling of tissue sections provides in situ molecular analysis of proteins and peptides. Analysis and visualization of these high-dimensional data cubes is challenging. We present a methodology for this task based on a novel developed algorithm for the feature identification and reduction step. To show the validity of our approach, we analyzed prostate cancer tissue sections with an adapted kernel-density based clustering algorithm.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
