抗生素骨水泥包被钉和骨水泥珠治疗感染性长骨不连的介入研究

P. Agrawal, N. Rajkumar, Murali Mothilal, SV Sunny Deol, V. A. Jothi
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摘要

背景:本研究旨在评估抗生素骨水泥包被钉和骨水泥珠治疗感染性长骨不连的疗效。材料与方法:本前瞻性介入研究于2010年6月至2012年8月在巴特那医学院骨科急诊科和门诊收治的长骨感染性不愈合病例中进行。所有植入物感染的肢体不愈合病例均被纳入研究。共纳入44例。数据分析使用SPSS版本17。结果:本组44例感染性骨不连中,感染治愈40例,偶有出院3例,连续出院1例。40例治愈患者行二次手术治疗,其中37例完全愈合,3例偶尔出院,无一例连续出院。结论:在感染性长骨不连病例中使用抗生素骨水泥包覆钉和骨水泥珠可显著减少伤口清创等进一步手术的需要。
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An Interventional Study on Antibiotic Cement-coated Nails and Cement Beads in the Management of Infected Nonunion of Long Bones
Background: The present study was aimed to assess the efficacy of antibiotic cement-coated nails and cement beads among the cases of infected nonunion of long bones. Materials and methods: This prospective interventional study was conducted among the cases admitted in the emergency and outpatient department of Orthopedics in Patna Medical College and Hospital, Patna, with infected nonunion of long bones, during the month of June 2010 to August 2012. All cases with an infected nonunion of extremities with implants were included. A total of 44 cases were included. Data analysis was done using SPSS version 17. Results: In this study, out of 44 infected nonunion, 40 were cured of infection, 3 cases had occasional discharge, and 1 case had a continuous discharge. Secondary procedures were done for the 40 cured cases and among them, 37 showed complete achievement of union, and 3 cases had occasional discharge and no case had a continuous discharge. Conclusion: The use of antibiotic cement-coated nails and cement beads among the cases with infected nonunion of long bones significantly reduced the requirement of a further surgical procedure like debridement of the wound site.
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