3.0T MR高b值DWIBS对脑转移灶的检测价值

Y. Wang, Qin-yan Xu, Ye Zhang, Xi-zhen Wang, Xi-he Sun, Yue Guan, Yan-ming Ge, Guang-hui Chang
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摘要

对比普通fa值、高b值DWIBS与增强成像的影像特征,探讨3.0T MR背景抑制高b值弥散加权成像(DWIBS)对脑转移灶的检测价值。收集经临床及病理证实的41例脑转移瘤患者。所有患者均行常规MRI和增强MRI检查,DWIBS采用普通b值(b= 0.1000 s/mm2)和高b值(b=3000s/mm2)两种b值类型。避开囊性坏死区,测量肿瘤实质及邻近正常白质的信号强度(SI)、背景噪声及表观扩散系数(ADC)值。根据这些数据计算信噪比(SNR)、噪声对比比(CNR)和对比度(CR)的平均值。高b值DWIBS病变诊断准确率优于普通b值DWIBS。高b值DWIBS序列脑转移灶的CNR、CR、si -病变/ si -正常值均显著高于普通b值DWIBS序列(P< 0.05)。信噪比显著低于普通b值DWIBS序列(P <;0.05)。T1WI增强脑组织的CNR、CR显著高于正常脑组织(P<;0.05)。高b值DWIBS序列的ADC值低于普通b值DWIBS序列(P <;0.05)。结论高b值DWIBS序列对脑转移瘤的检测具有重要价值。该方法简便,可避免造影剂对人体的潜在危害。
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The value of 3.0T MR high-b-value DWIBS in detecting the cerebral metastases
Comparing the imaging features on the ordinary fa-value and high-b-value DWIBS with that on the enhanced imaging, to explore the value of 3.0T MR high-b-value diffusion weighted imaging with background suppression (DWIBS) in detecting the cerebral metastases. 41 patients with cerebral metastases confirmed by clinically and pathologically were collected. All the patients underwent conventional MRI and contrast-enhanced MRI, and DWIBS used two types b-value: ordinary b-value (b=0, 1000s/mm2) and high-b-value (b=3000s/mm2). Evading cystic necrosis area, the signal intensity (SI), background noise and apparent diffusion coefficient (ADC) value of tumor parenchyma and adjacent normal white matter were measured. The averages of signal to noise ratio (SNR), contrast to noise ratio (CNR) and contrast ratio (CR) were computed from these data. The lesion diagnosis accuracy rate of high-b-value DWIBS was better than that of ordinary b-value. On high-b-value DWIBS sequence, the CNR, CR and SI-lesion/ SI-normal of brain metastasis was significant higher than that of ordinary b-value DWIBS sequence (P<;0.05). And the SNR was significant lower than that of ordinary b-value DWIBS sequence (P <; 0.05). The CNR, CR of Contrast-enhanced T1WI was significant higher than that of normal brain tissue (P<;0.05). The ADC value in High-b-value DWIBS sequence was lower than that in ordinary b-value DWIBS sequence (P <; 0.05). Conclusion High-b-value DWIBS sequence showed a great value in detecting cerebral metastases. It was a simple method and could be avoiding potential harm of contrast agent for the human bodies.
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