经颈静脉肝内门静脉大循环短路术(TIPS)对50例难治性腹水的治疗成绩

秀典 金沢, 義之 楢原, 健二 福田, 千紗 近藤, 滉智 張本, 洋子 松下, 秀子 城所, 玲樹 片倉, 正則 厚川, 保彦 滝, 祐 木村, 祐二 長田, 雄久 中塚, 長逸 坂本
{"title":"经颈静脉肝内门静脉大循环短路术(TIPS)对50例难治性腹水的治疗成绩","authors":"秀典 金沢, 義之 楢原, 健二 福田, 千紗 近藤, 滉智 張本, 洋子 松下, 秀子 城所, 玲樹 片倉, 正則 厚川, 保彦 滝, 祐 木村, 祐二 長田, 雄久 中塚, 長逸 坂本","doi":"10.11405/NISSHOSHI.106.356","DOIUrl":null,"url":null,"abstract":": In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"経頸静脈的肝内門脈大循環短絡術(TIPS)による難治性腹水50例の治療成績\",\"authors\":\"秀典 金沢, 義之 楢原, 健二 福田, 千紗 近藤, 滉智 張本, 洋子 松下, 秀子 城所, 玲樹 片倉, 正則 厚川, 保彦 滝, 祐 木村, 祐二 長田, 雄久 中塚, 長逸 坂本\",\"doi\":\"10.11405/NISSHOSHI.106.356\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.\",\"PeriodicalId\":341053,\"journal\":{\"name\":\"The Japanese journal of gastro-enterology\",\"volume\":\"65 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Japanese journal of gastro-enterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11405/NISSHOSHI.106.356\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Japanese journal of gastro-enterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11405/NISSHOSHI.106.356","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

在这项前瞻性队列研究中,我们评估了50例Child-Pugh评分为9.8分的难治性腹水患者使用经颈静脉肝内门系统分流术(TIPS)。平均随访时间为592天。1年后腹水改善96%,2年后腹水改善93%。1年、2年和5年的累计生存率分别为71%、52%和18%。TIPS治疗后Child-Pugh评分和表现状态评分均有显著提高。由于分流管狭窄,36例患者在随访期间需要进行分流管翻修。肝性脑病经医学控制的有26例。我们的研究结果表明,虽然可能需要分流修正,TIPS可以控制难治性腹水在大多数生存病例和改善生活质量。然而,我们的tips治疗的难治性腹水患者的5年生存率仍然很低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
経頸静脈的肝内門脈大循環短絡術(TIPS)による難治性腹水50例の治療成績
: In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
腸管スピロヘータ症(human intestinal spirochetosis;HIS)の臨床的意義についての検討 内視鏡的粘膜下層剥離術(endoscopic submucosal dissection)の1年10カ月後に異時性肝転移をきたした胃神経内分泌癌(neuroendocrine carcinoma)の1例 Trousseau症候群として発症した腸間膜への播種をともなった胃mucosa-associated lymphoid tissue(MALT)リンパ腫の1症例 Helicobacter pylori未感染の胃粘膜に生じた0-IIa+IIc型分化型癌の1例 Low-dose FP療法が奏効した切除不能混合型肝癌の1例
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1