Reply: Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.

1 Institute of Neuropathology, University Medical Center, Göttingen, Germany 2 Department of Neurosciences, Centre de recherche de l’Université de Montréal (CRCHUM), Montréal, Québec, Canada 3 Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, General Hospital Nuremberg, Paracelsus Medical University, Nuremberg, Germany 4 Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany 5 Department of Neurology, University of California, San Francisco, CA, USA 6 Department of Neurology, University Medical Center, Göttingen, Germany