印度尼西亚HIV患者心血管疾病的风险:文献综述

Ismail Fahmi
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摘要

摘要艾滋病是当今世界的一大健康问题。艾滋病毒感染具有降低免疫状态和增加心血管疾病风险的作用。使用抗逆转录病毒(ART)治疗艾滋病毒也会增加患心脏病的风险。目的:本文献综述旨在确定印度尼西亚HIV患者心血管疾病的风险。方法:检索关键词为“抗逆转录病毒治疗”、“心血管疾病”、“冠状动脉疾病”和“艾滋病毒”,对2009年1月至2018年9月发表的文章进行文献综述。结果:有21篇期刊文章与论文的设计和目的相关,有3篇文章讨论了印度尼西亚HIV患者的心脏病风险。文献综述的结果表明,印度尼西亚的艾滋病毒患者有发生心血管疾病的风险,而使用抗逆转录病毒治疗和吸烟行为会加剧这种风险。心血管疾病的风险包括结构异常和冠心病。结论:HIV患者发生心血管疾病的危险性较高。这对卫生工作者、政府和研究人员来说是一项挑战,他们需要制定适当的战略和方法来减少心血管疾病的风险,特别是在印度尼西亚等中低收入国家。关键词:抗逆转录病毒治疗,心血管疾病,艾滋病毒,艾滋病,印度尼西亚艾滋病毒
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Risk of cardiovascular disorders in HIV patients in Indonesia: Literature Review
Abstract HIV is a major health problem in the world. HIV infection has the effect of reducing immunity status and increasing the risk of cardiovascular disease. Antiretroviral (ART) use as a therapy for HIV also increases the risk of heart disease. Objective: This literature review aims to identify the risk of cardiovascular disorders in HIV patients in Indonesia. Method: literature review of articles published January 2009 to September 2018 using search keywords namely 'Anti-retroviral therapy', 'Cardiovascular disease', 'Corronary artery disease', and 'HIV'. Results: There were 21 journal articles that were relevant to the design and purpose of paper and 3 articles that discussed the risk of heart disease in HIV patients in Indonesia. The results of the literature review showed that HIV patients in Indonesia are at risk of developing cardiovascular disorders which are exacerbated by the use of ART and smoking behavior. The risk of cardiovascular disease includes structural abnormalities and coronary heart disease. Conclusion: HIV patients have a high risk of developing cardiovascular disease. This is a challenge for health workers, the government and researchers, to develop appropriate strategies and methods in reducing the risk of cardiovascular disorders especially in low-middle income country countries such as Indonesia. Keyword: Anti-retroviral therapy, cardiovascular disease, HIV, AIDS, HIV in Indonesia
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