{"title":"番石榴(Piper methysticum)成分的抗癌活性","authors":"J. Tabudravu, M. Jaspars","doi":"10.1071/SP05005","DOIUrl":null,"url":null,"abstract":"Crude extracts of kava (Piper methysticum G. Forster, Piperaceae) showed good activity against ovarian tumour and leukaemia cancer cell lines. Bioassay-guided isolation resulted in the isolation of six known kava lactones and two flavokavains. The structure of the compounds were elucidated by spectroscopic techniques and by comparison with data in the literature.","PeriodicalId":148381,"journal":{"name":"The South Pacific Journal of Natural and Applied Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2005-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"16","resultStr":"{\"title\":\"Anticancer activities of constituents of kava (Piper methysticum)\",\"authors\":\"J. Tabudravu, M. Jaspars\",\"doi\":\"10.1071/SP05005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Crude extracts of kava (Piper methysticum G. Forster, Piperaceae) showed good activity against ovarian tumour and leukaemia cancer cell lines. Bioassay-guided isolation resulted in the isolation of six known kava lactones and two flavokavains. The structure of the compounds were elucidated by spectroscopic techniques and by comparison with data in the literature.\",\"PeriodicalId\":148381,\"journal\":{\"name\":\"The South Pacific Journal of Natural and Applied Sciences\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The South Pacific Journal of Natural and Applied Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1071/SP05005\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The South Pacific Journal of Natural and Applied Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1071/SP05005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
摘要
卡瓦(Piper methysticum G. Forster，胡椒科)粗提物对卵巢癌和白血病癌细胞具有良好的抗肿瘤活性。生物测定引导分离得到6种已知的卡瓦内酯和2种黄烷素。化合物的结构通过光谱技术和与文献数据的比较得到了证实。
Anticancer activities of constituents of kava (Piper methysticum)
Crude extracts of kava (Piper methysticum G. Forster, Piperaceae) showed good activity against ovarian tumour and leukaemia cancer cell lines. Bioassay-guided isolation resulted in the isolation of six known kava lactones and two flavokavains. The structure of the compounds were elucidated by spectroscopic techniques and by comparison with data in the literature.
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