{"title":"优化子宫颈癌的放射治疗","authors":"Rachelle Lanciano MD","doi":"10.1016/S0039-6109(05)70170-5","DOIUrl":null,"url":null,"abstract":"<div><div><span>Since the 1920s, radiation has been used to effectively treat and cure cervical cancer. Major developments in radiation oncology<span> technology have led to more accurate simulation of treatment fields with CT-based treatment planning and improved dose distribution of external beam radiation therapy<span> (EBRT) to the target by linear-accelerator produced high-energy photons, three-dimensional treatment-planning systems, and conformal blocking techniques. The need for dose intensity with brachytherapy and reduction of overall treatment time has been established. This article reviews the technical factors of radiation for cervical cancer and explores ways to optimize dose delivery. Results of recently reported phase 3 trials of </span></span></span>cisplatin<span> containing chemoradiation regimens are discussed because their use has optimized pelvic control and survival for cervical cancer.</span></div></div>","PeriodicalId":54441,"journal":{"name":"Surgical Clinics of North America","volume":"81 4","pages":"Pages 859-870"},"PeriodicalIF":2.8000,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"OPTIMIZING RADIATION TREATMENT FOR CERVICAL CANCER\",\"authors\":\"Rachelle Lanciano MD\",\"doi\":\"10.1016/S0039-6109(05)70170-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><span>Since the 1920s, radiation has been used to effectively treat and cure cervical cancer. Major developments in radiation oncology<span> technology have led to more accurate simulation of treatment fields with CT-based treatment planning and improved dose distribution of external beam radiation therapy<span> (EBRT) to the target by linear-accelerator produced high-energy photons, three-dimensional treatment-planning systems, and conformal blocking techniques. The need for dose intensity with brachytherapy and reduction of overall treatment time has been established. This article reviews the technical factors of radiation for cervical cancer and explores ways to optimize dose delivery. Results of recently reported phase 3 trials of </span></span></span>cisplatin<span> containing chemoradiation regimens are discussed because their use has optimized pelvic control and survival for cervical cancer.</span></div></div>\",\"PeriodicalId\":54441,\"journal\":{\"name\":\"Surgical Clinics of North America\",\"volume\":\"81 4\",\"pages\":\"Pages 859-870\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2001-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical Clinics of North America\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0039610905701705\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2005/5/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical Clinics of North America","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0039610905701705","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2005/5/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}
OPTIMIZING RADIATION TREATMENT FOR CERVICAL CANCER
Since the 1920s, radiation has been used to effectively treat and cure cervical cancer. Major developments in radiation oncology technology have led to more accurate simulation of treatment fields with CT-based treatment planning and improved dose distribution of external beam radiation therapy (EBRT) to the target by linear-accelerator produced high-energy photons, three-dimensional treatment-planning systems, and conformal blocking techniques. The need for dose intensity with brachytherapy and reduction of overall treatment time has been established. This article reviews the technical factors of radiation for cervical cancer and explores ways to optimize dose delivery. Results of recently reported phase 3 trials of cisplatin containing chemoradiation regimens are discussed because their use has optimized pelvic control and survival for cervical cancer.
期刊介绍：
Surgical Clinics of North America has kept surgeons informed on the latest techniques from leading surgical centers worldwide. Each bimonthly issue (February, April, June, August, October, and December) is devoted to a single topic relevant to the busy surgeon, with articles written by experts in the field. Case studies and complete references are also included to give you the most thorough data you need to stay on top of your practice. Topics include general surgery, alimentary surgery, abdominal surgery, critical care surgery, trauma surgery, endocrine surgery, breast cancer surgery, transplantation, pediatric surgery, and vascular surgery.
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