Michael Okpara农业大学(Mouau)诊所和Madonna Catholic Hospital Umuahia, abbia州患者中乙型肝炎的患病率

I. Nwankwo, K. Edward, G. Chukwuma, C. Udensi, M.C. Ofia
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摘要

目的:确定Michael Okpara农业大学(MOUAU)诊所和阿比亚州Umuahia圣母天主教医院患者中乙型肝炎的患病率。使用无菌注射器和针头无菌采集血样。每位患者采集约2-5ml血液并用冰袋送到微生物实验室进行疫苗接种前检测。根据制造商的说明,使用Smart Check HBsAg (Globalemed, Cape Town, South Africa)进行HBsAg的现场检测。本研究显示,约46.5%的研究参与者乙型肝炎表面抗原呈阳性,而乙型肝炎表面抗原在男性和女性患者中的年龄分布显示,乙型肝炎表面抗原在16-34岁的患者中发病率最高,患病率为19%(55.9%)。研究还发现,女性患者中乙型肝炎病毒感染率最高,阳性率为47.7%。HBsAg在16-34岁年龄组的流行率高于其他年龄组。如此高的流行率要求提高对尼日利亚有效乙肝表面抗原免疫规划的认识。疫苗接种在抗击乙型肝炎中的重要性再怎么强调也不为过,强调有必要对研究年龄组的所有人进行普遍免疫接种,并制定预防母婴传播的措施。因此,建议尼日利亚在乙型肝炎疫苗时代之前出生的青少年接受公共卫生教育和预防感染的疫苗接种。
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Prevalence of hepatitis B among patients in Michael Okpara University of Agriculture, (Mouau) Clinic and Madonna Catholic Hospital Umuahia, Abia State
To determine the prevalence of Hepatitis B among patients in Michael Okpara University of Agriculture, (MOUAU) clinic and Madonna Catholic Hospital Umuahia, Abia State. Blood samples were collected aseptically using a sterile syringe and needle. About 2-5ml of blood was collected from each patient and conveyed in ice packs to Microbiology Laboratory for pre-vaccination tests. On-the-spot testing for HBsAg was conducted using Smart Check HBsAg (Globalemed, Cape Town, South Africa) according to the manufacturer’s instructions. This study revealed that about 46.5% of the study participants were positive for hepatitis B surface antigen, while the prevalence of age distribution of Hepatitis B surface antigen among male and female patients revealed that the rate of Hepatitis B Surface Antigen was highest in patients between the age 16-34 years at a percentage prevalence of 19(55.9%). This study also revealed that Hepatitis B virus prevalence rates were the most prevalent among female patients with a positive percentage value of 47.7%.The prevalence rate of HBsAg was higher in the 16-34 age group than in the other age groups tested. This high prevalence rate calls for more awareness on effective HBsAg immunization program in Nigeria. The importance of vaccination in the fight against hepatitis B cannot be overstated, emphasizing the necessity for universal immunization of all people in the study's age group and the creation of measures to prevent mother-to-child transmission. As a result, it is advised that adolescents born before the hepatitis B vaccine era in Nigeria receive public health education and vaccination against the infection.
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