磁共振成像对肌肉减少症的评估

K. Bisyri, G. Lambrou
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引用次数: 1

摘要

智力下降,跌倒、骨折和住院的风险增加。虽然可以通过专门的问卷填写和临床测试表现来识别肌少症,但影像学通过对肌肉质量和数量的估计对肌少症的诊断有决定性的作用。有多种成像方法可用于此目的,如超声检查、双能射线吸收仪、计算机断层扫描和磁共振成像(MRI)。这篇综述的目的是介绍MRI在肌肉减少症评估中的应用,通过突出这种成像方式的优势,特定的MRI衍生替代参数/肌肉减少症的生物标志物以及服务于该范围的MRI技术。摘要肌少症是一种与衰老交织的多因素发病的定性和定量肌肉疾病。对日常生活和功能能力的负面影响是显著的,并最终导致总生存率的降低。各种先进的磁共振成像技术使及时发现和表征疾病成为可能,从而有助于改善共存疾病的预后。
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The assessment of sarcopenia using magnetic resonance imaging
mental decline, increased risk for falls, fractures and hospitalization. Even though recognizing sarcopenia can be done through a special questionnaire filling in and clinical test performance, imaging plays a determinant role in sarcopenia’s diagnosis confirmation by estimating the muscle quality and quantity. There are various imaging methods that can be used for this purpose, such us ultrasonography, dual energy-ray absorptiometry, computed tomography and Magnetic Resonance Imaging (MRI) 5 . The aim of this review is to present the applications of MRI in sarcopenia assessment, by giving prominence to the advantages of this imaging modality, the specific MRI-derived surrogate parameters/biomarkers of sarcopenia and the MRI techniques serving that scope. Abstract Sarcopenia is a quantitative and qualitative muscle disorder with multifactorial pathogenesis intertwining with aging. The negative consequences on everyday life and functional ability are significant and have as final result the reduction of overall survival. Various and advanced magnetic resonance imaging techniques make prompt detection and disease characterization feasible, thus contribute to the modification of coexistent diseases prognosis.
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