重度抽动秽语综合征患者电休克治疗过程中的程序巩固。

R. Katz, E. Bukanova, R. Ostroff
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引用次数: 1

摘要

刺激能量设置为100%。用于电痉挛治疗的麻醉剂包括静脉注射甲氧己酮90毫克和静脉注射琥珀碱100毫克。患者经历了3次电痉挛发作,尽管血压和心率变化通常与癫痫发作活动相关,但缺乏适当的脑电图癫痫发作持续时间记录。在每次发作期间,患者给予地尔硫卓缓释片180mg /天治疗。在停用地尔硫卓并同时切换到双颞叶刺激电极放置后,治疗引起的癫痫发作开始达到更可预测的持续时间。地尔硫卓似乎妨碍了癫痫的全面电痉挛治疗。Wajima等比较了18例每日静脉注射地尔硫卓10mg或安慰剂组的患者,发现地尔硫卓组脑电图发作时间明显缩短(P < 0.05)。这些患者也表现出可预测的血流动力学增加,这正是在本报告的患者病例中观察到的。维拉帕米,另一种非二氢吡啶类钙通道阻滞剂,在接受ECT治疗的患者中与安慰剂比较,发现癫痫发作持续时间没有减少,所以这种现象不一定是类特异性的。
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Procedural Consolidation During Electroconvulsive Therapy for a Patient With Severe Tourette Syndrome.
with stimulus energies set to 100%. Anesthetic agents used for the ECT procedures included methohexital 90 mg intravenous and succinylcoline 100 mg intravenous. The patient experienced 3 ECT episodes that lacked appropriate EEG seizure duration documentation despite blood pressure and heart rate changes typically associated with seizure activity. During each of these episodes, the patient was being treated with diltiazem extended-release 180 mg daily. Upon discontinuation of diltiazem and concurrent switch to bitemporal stimulus electrode placement, the treatment-induced seizures began to reach more predictable durations. Diltiazem seemed to interfere with achieving full ECT treatment seizures. Wajima et al compared 18 patients taking diltiazem 10 mg intravenous daily or placebo and reported a significantly shorter EEG seizure duration in the diltiazem group (P < 0.05). These patients also exhibited predictable increases in hemodynamics, which was precisely what was observed in this reported patient case. Verapamil, another nondihydropyridine calcium channel blocker, was compared with placebo in patients undergoing ECT and found no reduction of seizure duration, so this phenomenon is not necessarily class specific.
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