BOBBY球囊引导导管大血管闭塞性脑卒中取栓:初步经验。

Karan K. Topiwala, C. Quinn, T. Mehta, K. Masood, A. Grande, R. Tummala, B. Jagadeesan
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引用次数: 4

摘要

背景与目的非随机研究发现球囊导尿管(BGC)可以改善机械取栓(MT)患者的技术和功能结果。材料与方法我们对我院(2020年12月- 2021年10月)连续接受MT治疗的缺血性脑卒中患者前瞻性收集的数据进行回顾性分析。确定采用BOBBY BGC (BBGC, MicroVentionTM, Aliso Viejo, CA)的干预措施。回顾性收集基线人口统计学和临床放射学特征,并使用描述性统计进行分析。结果共43例患者接受了BBGC-MT治疗(男:女= 26:17,中位年龄72岁[IQR 62-82])。最常见的闭塞部位是大脑中动脉(MCA)(60.4%)。超过一半(51.2%)的患者接受静脉溶栓治疗。BBGC在弯曲的主动脉弓上追踪良好(II型34.8%,III型16.3%),中位动脉切开至灌注时间为29分钟(IQR 20-46)。69.7%的患者采用血栓抽吸作为一线MT技术,1 (IQR 1-2) MT中位通过分别为74.4%和95.3%的患者达到改良TICI(脑缺血溶栓)评分3分和2b/3分。我们的总体一过效应(FPE,定义为第一次通过后的mTICI 3)和改进的FPE(定义为第一次通过后的mTICI 2b/3)率分别为51.1%和79.1%,当扩张术和血栓抽吸联合使用时分别为92.3%和100%。美国国立卫生研究院卒中量表(NIHSS)中位下降为9 (IQR 4-15, p < 0.0001), 90天修正Rankin评分(mRS)中位下降为1.5 (IQR 0-2)。结论使用bobby BGC可获得较高的一次通过率,并可能有助于改善功能预后。
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BOBBY balloon guide catheter thrombectomy in large-vessel occlusion stroke: Initial experience.
BACKGROUND AND PURPOSE Nonrandomized studies have found Balloon Guide Catheter (BGC) use to improve technical and functional outcomes in patients undergoing mechanical thrombectomy (MT). MATERIALS AND METHODS We performed a retrospective analysis on prospectively collected data of consecutive ischemic stroke patients undergoing MT at our institution (December 2020-October 2021). Interventions where BOBBY BGC (BBGC, MicroVentionTM, Aliso Viejo, CA) was used were identified. Baseline demographics and clinico-radiographic characteristics were retrospectively collected and analysed using descriptive statistics. RESULTS A total of 43 patients received BBGC-MT (male: female = 26:17, median age 72 years [IQR 62-82]). The most common occlusion site was the middle cerebral artery (MCA) (60.4%). Over half (51.2%) received intravenous thrombolytics. The BBGC tracked well over tortuous aortic arches (type II 34.8%, type III 16.3%), with median arteriotomy-to-perfusion time of 29 min (IQR 20-46). Thromboaspiration was used as first-line MT technique in 69.7% cases, with 1 (IQR 1-2) median MT pass achieving modified TICI (thrombolysis in cerebral ischemia) scores of 3 and 2b/3 in 74.4% and 95.3% respectively. Our overall first pass effect (FPE, defined as mTICI 3 after firs-pass) and modified FPE (defined as, mTICI 2b/3 after first-pass) rates were 51.1% and 79.1% respectively, with rates of 92.3% and 100% respectively when stentretriever and thromboaspiration were combined. The median reduction in National Institutes of Health Stroke Scale (NIHSS) was 9 (IQR 4-15, p < 0.0001), with a median 90-day modified Rankin Score (mRS) of 1.5 (IQR 0-2). CONCLUSIONS BOBBY BGC use resulted in a high first-pass effect rate and may contribute towards improved functional outcomes.
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