丛状纤维组织细胞瘤。

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247703
F Giard, R Bonneau, G P Raymond
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引用次数: 11

摘要

在丛状纤维组织细胞肿瘤中发现两组细胞,一组呈圆形或椭圆形,另一组呈纺锤形。在这两种类型的大多数细胞中,α -平滑肌肌动蛋白免疫组化阳性,但在梭形细胞中阳性,提示其起源于肌成纤维细胞。电镜显示成纤维细胞、肌成纤维细胞和一些未分化的间充质细胞。然而,因子XIIIa为阴性,提示该肿瘤并非起源于真皮树突细胞。
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Plexiform fibrohistiocytic tumor.

Two groups of cells, one rounded or oval and the other spindle-shaped, were found in a case of plexiform fibrohistiocytic tumor. Immunohistochemistry was strongly positive for alpha smooth muscle actin in most cells of both types but stronger in the spindle-shaped cells, suggesting a myofibroblastic origin. This was in correlation with electron microscopic findings which revealed fibroblasts, myofibroblasts and some undifferentiated mesenchymal cells. However, factor XIIIa was negative suggesting that this tumor does not originate from dermal dendrocytes.

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