微波频率下正常和恶性乳腺组织的介电特性:威斯康星/卡尔加里研究的分析、结论和意义

M. Lazebnik, C. B. Watkins, S. Hagness, J. Booske, D. Popovic, L. Mccartney, M. Okoniewski, M. Lindstrom, T. Breslin, J. Harter, S. Sewall, W. Temple, D. Mew, A. Magliocco, T. Ogilvie
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引用次数: 16

摘要

新兴的微波乳腺癌检测及热疗技术的临床疗效(见[X]。李等,2005],[M]。Converse等[2004]及相关文献)取决于正常、恶性和良性乳腺组织的微波介电特性。对这些特性的了解受到先前发表的关于癌症手术后获得的正常和恶性乳腺组织介电特性的小规模研究的空白和差异的限制[L]。Sha et al., 2002]。为了解决这些限制,我们在威斯康星大学和卡尔加里大学进行了一项大规模的联合研究,实验表征了从乳房缩小手术和癌症手术中获得的新鲜切除的正常、良性和恶性乳腺组织在微波频率(0.5至20 GHz)下的宽带介电特性。在我们的报告中,我们将强调我们完成的研究的各个方面的结论。由于本次会议论文摘要的篇幅限制,这里我们将重点介绍通过复位手术和癌症手术获得的正常乳腺组织介电特性的比较结果。
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The dielectric properties of normal and malignant breast tissue at microwave frequencies: analysis, conclusions, and implications from the wisconsin/calgary study
The clinical efficacy of emerging microwave breast cancer detection and hyperthermia treatment techniques (see [X. Li et al., 2005], [M. Converse et al., 2004] and references therein) depend on the microwave dielectric properties of normal, malignant, and benign breast tissues. Knowledge of these properties has been limited by gaps and discrepancies in previously published small-scale studies reporting the dielectric properties of normal and malignant breast tissues obtained from cancer surgeries [L. Sha et al., 2002]. To address these limitations, we have conducted a large-scale joint study at the Universities of Wisconsin and Calgary to experimentally characterize the wideband dielectric properties at microwave frequencies (from 0.5 to 20 GHz) of freshly excised normal, benign, and malignant breast tissues obtained from breast reduction as well as cancer surgeries. In our presentation, we will highlight the conclusions from all aspects of our completed study. Due to space limitations in this conference paper summary, here we focus on the results of a comparison of the dielectric properties of normal breast tissues obtained from both reduction and cancer surgeries.
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