采用改进主观整体评价评分法评价老年血透患者营养状况

A. Mahmoud, S. Afifi, S. Shalaby, Said M. Al-Barshomy
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We aimed to assess the nutritive status of the elderly patients with end-stage renal disease (ESRD) undergoing hemodialysis using modified subjective global assessment score (M-SGAS) and to correlate between it and different biochemical parameters. Patients and methods A total of 100 ESRD elderly patients on regular hemodialysis were included. All patients were subjected to the following: history taking, including weight change, dietary intake, gastrointestinal symptoms, and functional capacity (nutritionally related functional impairments, comorbidity); physical examination, including decreased fat stores or loss of subcutaneous fat (eyes, triceps, biceps, and chest), signs of muscle wasting (temple, clavicle, ribs, knee, interosseous, quadriceps, and scapula), mid-upper arm and calf circumference, and BMI; malnutrition score (sum of all number) using SGAS; and laboratory investigations, including complete blood count, serum creatinine, blood urea, C-reactive protein, serum albumin, parathyroid hormone, serum calcium, serum phosphorus. urea reduction ratio, and KT/V. Results There was a decrease in anthropometric measures in both males and females, indicating that both sexes are prone to malnutrition to the same degree. On comparing between male and female patients with respect to total M-SGAS, they lie in the moderate degree of total M-SGAS, with no significant difference between males and females. There was a statistically significant negative correlation between M-SGAS and triceps skin fold, mid-arm muscle circumference, and mid-arm circumference, and also there was a statistically significant negative correlation between duration of dialysis and mid-arm circumference. Conclusion The M-SGAS can be used as reliable, rapid, and precise method for nutritional assessment in elderly patients with ESRD on regular hemodialysis. There is a high prevalence of malnutrition among all age groups, even those younger than 40 years old. Malnutrition is associated with female sex, hypoalbuminemia, increased inflammatory markers such as elevated C-reactive protein and elevated total leukocytic count, and in those with low hemoglobin level. 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引用次数: 0

摘要

营养不良是老年医学中的一个重要问题,在血液透析患者中越来越被认识到,它甚至可以恶化这些患者的预后和生活质量。当务之急是肾病学界认识到这种营养不良综合征,并努力管理它。营养不良通常可以在透析患者的所有年龄组中检测到,它是比实际年龄更好的发病率和死亡率的敏感标志。它也可能是透析患者抑郁和认知障碍发展的主要辅助因素。我们的目的是利用改良的主观整体评估评分(M-SGAS)评估接受血液透析的老年终末期肾病(ESRD)患者的营养状况,并探讨其与不同生化参数之间的相关性。患者与方法入选100例定期血液透析的ESRD老年患者。所有患者均接受以下检查:病史记录,包括体重变化、饮食摄入、胃肠道症状和功能能力(营养相关功能障碍、合并症);体格检查,包括脂肪储存减少或皮下脂肪减少(眼睛、三头肌、二头肌和胸部),肌肉萎缩的迹象(太阳穴、锁骨、肋骨、膝盖、骨间、股四头肌和肩胛骨),上臂和小腿围,BMI;营养不良评分(所有数字之和)采用SGAS;和实验室调查,包括全血细胞计数、血清肌酐、尿素、c反应蛋白、血清白蛋白、甲状旁腺激素、血清钙、血清磷。尿素还原比,KT/V。结果男性和女性的人体测量值均有下降,表明两性都有相同程度的营养不良倾向。在M-SGAS总量上,男女患者比较,均处于中等程度的M-SGAS总量,男女之间无显著差异。M-SGAS与肱三头肌皮肤褶、臂中肌围、臂中围呈显著负相关,透析时间与臂中围呈显著负相关。结论M-SGAS可作为老年ESRD定期血液透析患者营养评价的可靠、快速、准确的方法。营养不良在所有年龄组中都很普遍,甚至在40岁以下的年龄组中也是如此。营养不良与女性、低白蛋白血症、炎症标志物(如c反应蛋白升高和白细胞总数升高)增加以及血红蛋白水平低的人有关。甲状旁腺功能亢进症患者也更容易发现营养不良。
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Evaluation of nutritional status of regular hemodialysis elderly patients using modified subjective global assessment score
Background Malnutrition, an important problem in geriatric medicine, is becoming more recognized in hemodialysis patients, as a factor that can even worsen the prognosis and the quality of life of these patients. It is imperative for the nephrology community to recognize this syndrome of malnutrition and work to manage it. Malnutrition can be detected commonly in all age groups of dialysis patients, and it represents a sensitive marker for morbidity and mortality better than chronological age. It could also act as a major cofactor for depression and cognitive impairment development in dialysis patients. We aimed to assess the nutritive status of the elderly patients with end-stage renal disease (ESRD) undergoing hemodialysis using modified subjective global assessment score (M-SGAS) and to correlate between it and different biochemical parameters. Patients and methods A total of 100 ESRD elderly patients on regular hemodialysis were included. All patients were subjected to the following: history taking, including weight change, dietary intake, gastrointestinal symptoms, and functional capacity (nutritionally related functional impairments, comorbidity); physical examination, including decreased fat stores or loss of subcutaneous fat (eyes, triceps, biceps, and chest), signs of muscle wasting (temple, clavicle, ribs, knee, interosseous, quadriceps, and scapula), mid-upper arm and calf circumference, and BMI; malnutrition score (sum of all number) using SGAS; and laboratory investigations, including complete blood count, serum creatinine, blood urea, C-reactive protein, serum albumin, parathyroid hormone, serum calcium, serum phosphorus. urea reduction ratio, and KT/V. Results There was a decrease in anthropometric measures in both males and females, indicating that both sexes are prone to malnutrition to the same degree. On comparing between male and female patients with respect to total M-SGAS, they lie in the moderate degree of total M-SGAS, with no significant difference between males and females. There was a statistically significant negative correlation between M-SGAS and triceps skin fold, mid-arm muscle circumference, and mid-arm circumference, and also there was a statistically significant negative correlation between duration of dialysis and mid-arm circumference. Conclusion The M-SGAS can be used as reliable, rapid, and precise method for nutritional assessment in elderly patients with ESRD on regular hemodialysis. There is a high prevalence of malnutrition among all age groups, even those younger than 40 years old. Malnutrition is associated with female sex, hypoalbuminemia, increased inflammatory markers such as elevated C-reactive protein and elevated total leukocytic count, and in those with low hemoglobin level. Malnutrition also is more detected in patients with hyperparathyroidism.
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