使用科学工作流程的虚拟显微镜和分析

D. Abramson, B. Bethwaite, M. N. Dinh, C. Enticott, Stephen Firth, S. Garic, I. Harper, M. Lackmann, H. Nguyen, Tirath Ramdas, A. Russel, Stefan Schek, Mary Vail
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引用次数: 6

摘要

大多数商用显微镜都是由专用计算机系统控制的独立仪器。它们提供有限的存储和处理能力。另一方面,虚拟显微镜将图像捕获硬件和数据分析软件连接到一个由高性能计算机、大型存储设备和软件系统组成的广域网中。在本文中,我们讨论了网格工作流引擎的扩展,使他们能够在虚拟显微镜上执行科学实验。我们在一个生物医学案例研究中展示了这种系统的效用,该研究涉及癌症成像和基于抗体的治疗。
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Virtual Microscopy and Analysis Using Scientific Workflows
Most commercial microscopes are stand-alone instruments, controlled by dedicated computer systems. These provide limited storage and processing capabilities. Virtual microscopes, on the other hand, link the image capturing hardware and data analysis software into a wide area network of high performance computers, large storage devices and software systems. In this paper we discuss extensions to Grid workflow engines that allow them to execute scientific experiments on virtual microscopes. We demonstrate the utility of such a system in a biomedical case study concerning the imaging of cancer and antibody based therapeutics.
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