1-3月龄和4-6月龄母乳婴儿血清白蛋白水平的比较

N. Mudjihartini
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摘要

背景:血清白蛋白是血液中含量最丰富的血浆蛋白,有助于维持胶体渗透压,结合血浆中难溶物质,使其分布到全身。母乳中的血清白蛋白水平会受到各种因素的影响,如哺乳期(婴儿的年龄)、胎次数、母亲的年龄和体重指数(BMI)。本研究旨在确定母乳喂养1-3月龄婴儿和4-6月龄婴儿的母亲血清白蛋白水平的比较,并寻找其与母亲胎次、年龄和BMI的关系。方法:横断面设计实验研究,从Petamburan和Cilincing卫生中心的58名母亲中获得作为储存生物液体的母乳样本。用溴甲酚绿(BCG)试剂盒检测血清白蛋白水平。结果:哺乳期早期,即1-3月龄母乳血清白蛋白水平明显高于4-6月龄组(p=0.002)。1-3月龄婴儿母乳中血清白蛋白水平与母亲胎次(p=0.428)和母亲年龄(p=0.881)无相关性,但与母亲BMI呈显著正相关(p=000)。4-6月龄组母乳血清白蛋白水平与母亲胎次(p=0.823)和母亲年龄(p=0.581)无相关性,但与母亲体重指数(p=0.000)呈正相关。结论:母乳血清白蛋白水平受泌乳期(婴儿年龄)的影响,即1-3月龄的婴儿比4-6月龄的婴儿明显升高。母乳中血清白蛋白水平与母亲的身体质量指数有关,随着母亲身体质量指数的增加而升高。
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Comparison of Serum Albu-min Levels in The Breast Milk of Breastfeeding Infants Aged 1-3 Months and 4-6 Months
Background: Serum albumin is the most abundant plasma protein in the blood, contributing to maintaining colloid osmotic pressure and binding substances that are poorly soluble in plasma so that they can be distributed throughout the body. Serum albumin levels in breast milk can vary, influenced by various factors such as the lactation phase (age of the baby), number of parities, age and body mass index (BMI) of the mother. This study aims to determine the comparison of serum albumin levels in breast milk of mothers who breastfeed infants aged 1-3 months and 4-6 months and to find the relationship with the number of parities, age and BMI of the mother. Method: Cross-sectional design experimental study, breast milk samples as stored biological fluids were obtained from 58 mothers at the Petamburan and Cilincing Health Centers. Serum albumin levels were measured with the Bromocresol Green (BCG) kit. Results: The results showed that breast milk in the earlier lactation period, namely at 1-3 months, had significantly higher serum albumin levels compared to the serum albumin levels in the 4-6 months age group (p=0.002). Serum albumin levels in breast milk for infants aged 1-3 months did not correlate with mother's parity (p=0.428) and mother's age (p=0.881), but had a significant positive correlation with mother's BMI (p=000). Serum albumin levels in breast milk in the 4-6 months age group did not correlate with mother's parity (p=0.823) and mother's age (p=0.581) but had a strong positive correlation with maternal BMI (p=0.000). Conclusion: Breast milk serum albumin levels are affected by the lactation phase (age of the baby), namely at the age of 1-3 months the baby increases significantly compared to the age of 4-6 months. The level of serum albumin in breast milk is related to the mother's BMI, which increases with increasing mother's BMI.
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