深度度量学习与三重网络:应用于手部肌强直量化

Lei Lin, Beilei Xu, Wencheng Wu, Trevor W. Richardson, Edgar A. Bernal, Bill Martens, C. Thornton, C. Heatwole
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引用次数: 1

摘要

肌强直是指收缩后肌肉松弛延迟,是肌强直营养不良患者的主要症状。握紧手后的放松时间已被用作诊断目的的生物标志物,并在临床试验中用于量化治疗效果。目前依赖于手工特征的过程往往对数据采集噪声和患者内部和患者之间的可变性很敏感。在这项工作中,我们开发了一个基于三重网络的深度度量学习框架,用于分析手部握力时间序列。实验表明,学习嵌入空间可用于量化症状、评估治疗效果和设计新的数据收集方案。
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Deep Metric Learning with Triplet Networks: Application to Hand-grip Myotonia Quantification
Myotonia, which refers to delayed muscle relaxation after contraction, is the main symptom of myotonic dystrophy patients. The relaxation time after a hand squeeze has been used as a biomarker for diagnostic purposes and in clinical trials to quantify the effectiveness of a treatment. Current processes that rely on handcrafted features tend to be sensitive to data acquisition noise and intra- and inter-patient variability. In this work, we develop a deep metric learning framework for analyzing the hand-grip time series based on triplet-networks. Experiments show that the learned embedding space can be used to quantify the symptoms, evaluate the effectiveness of treatments, and design new data collection protocols.
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