双侧子宫动脉结扎与间歇夹紧子宫和卵巢动脉对腹部子宫肌瘤切除术出血量的影响:一项随机对照试验

H. Fathi, Haitham El Sabae, A. M. Elkotb, Yasmine Mohamed
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摘要

背景:子宫肌瘤切除术比子宫切除术更常见,主要是由于患者在完成家庭后,出于心理、生殖和文化原因,希望保留子宫。子宫肌瘤切除术的平均失血量为200 ~ 800ml。手术出血可导致贫血、低血容量和凝血异常。目的:比较双侧子宫动脉结扎术与子宫卵巢动脉间歇夹持术对子宫肌瘤切除术出血量的影响。患者与方法:本研究在Ain-Shams大学妇产医院对90例经后表现为子宫异常出血、下腹痛钝痛、性交困难、压力症状、进行性腹部增大或盆腔沉重,经临床检查及超声检查诊断,术前血红蛋白水平大于10gm/dl的有症状性肌瘤妇女进行研究。结果:两组术前Hb分别为11.6 gm%和11.8gm%,术后Hb分别为9.4 gm%和9.2 gm%。两组术后血红蛋白下降无显著性差异,夹紧组为0.8 gm%,结扎组为1.1 gm%。钳夹组术中估计失血量开始明显少于结扎组。夹紧组血红蛋白降低明显低于结扎组。结论:根据本研究结果,间歇夹紧子宫和卵巢动脉比双侧子宫动脉结扎术更适合子宫肌瘤切除术出血量。
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The effect of bilateral uterine artery ligation versus intermittent clamping of uterine and ovarian artery on blood loss during abdominal myomectomy : A randomized controlled trial
Background: Myomectomies are more commonly performed than hysterectomies, mainly due to the fact that patients desire to retain their uterus for psychological, reproductive and cultural reasons even after completing their families. The average volume of blood loss during abdominal myomectomy is 200 to 800 mL. Surgical hemorrhage may result in anemia, hypovolemia, and coagulation abnormalities.Aim: To compare between bilateral uterine artery ligation and intermittent clamping of uterine and ovarian artery on amount of blood loss during abdominal myomectomy.Patients and Methods: This study was conducted at Ain-Shams University Maternity Hospital on 90 women with symptomatic myomas in the postmenstrual period presented by abnormal uterine bleeding, dull aching lower abdominal pain, dyspareunia, pressure symptoms, progressive abdominal enlargement or pelvic heaviness, diagnosed based on clinical examination and ultrasound scan with pre-operative hemoglobin level above 10gm/dl.Results: The preoperative Hb was 11.6 gm % and 11.8gm% for both clamping and ligation one respectively, and post-operative Hb for the groups was 9.4 gm% and 9.2 gm% for the 2 groups respectively. There was no significant difference between both groups regarding postoperative drop of hemoglobin which was 0.8 gm % in the clamping group and 1.1 gm% in the ligation group. Estimated inraoperative blood loss start was significantly fewer among clamping group than among ligation group. Hemoglobin reduction was significantly fewer among clamping group than among ligation group.Conclusion: Based on the results obtained by this study, intermittent clamping of uterine and ovarian artery is a preferred approach than bilateral uterine artery ligation on blood loss during abdominal myomectomy.
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