膜蛋白的数据挖掘与知识发现

J.Y. Yang, M. Qu Yang, O. Ersoy
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引用次数: 1

摘要

生物信息学中的许多核心问题都与蛋白质的结构和功能有关。我们主要关注三个问题:蛋白质跨膜片段的识别,无序区与有序区的区分,以及从序列信息中确定蛋白质的功能。为了有效地解决这些问题,我们对构成蛋白质的氨基酸的理化性质和各类蛋白质的氨基酸组成进行了深入的分析。我们从机器学习的角度来解决上述问题
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Data mining and knowledge discovery from membrane proteins
Many of the central questions in bioinformatics relate to protein structure and function. We are mainly be concerned with three problems: identifying transmembrane segments in proteins, distinguishing disordered from ordered regions, and determining protein function from sequence information. In order to deal effectively with these problems, we have conducted an in-depth analyses of the physiochemical properties of the amino acids that make up proteins and the amino acid compositions of the various types of proteins. We approach the above questions from a machine learning perspective
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