KCOT /OKC clinical-molecular pathogenesis, surgical treatment & prognosis: A review

Odontogenic keratocysts (OKCs) are epithelial developmental cysts. It occurs Mainly in the second and third decades, with a slight predilection for males Usually, OKCs are solitary lesions. They may occur mostly in the Mandible; most commonly in the posterior body and Ascending ramus. Radiographically, OKCs present as A well defined radiolucent lesions with smooth and corticated margins. They may present as a Multilocular or unilocular radiolucent lesion. In most of the cases, there is an unerupted tooth involved with the Lesion.OKC’s is one of the most aggressive odontogenic Cysts due to its high recurrence rate and its tendency to invade adjacent tissue. Treatment Approaches vary in different studies from marsupialization and enucleation, which may be combined with Adjuvant therapy such as cryotherapy or Carnoy’s solution, BIPP to marginal or radical resection.