The Role of New MRI Modalities in Diagnosis of Multiple Sclerosis

Background : Although clinical data are still used to suspect multiple sclerosis (MS), MRI is now included in the disease ' s clinical prognosis. Aim : To evaluate the clinical importance of recent MRI techniques in MS. Patients and methods : This study was conducted on 20 patients of both sexes having MS. All patients were evaluated by full history taking,clinical assessment, and MRI examination includingrecent MRI modalities; double inversion recovery (DIR); spectroscopy; fl uid-attenuatedinversionrecovery(FLAIR)inaxial,sagittal,andcoronalplanes;anddiffusiontensorimaging. Results : We found that DIR and T2-weighted turbo spin echo (T2W-TSE) differed signi fi cantly from FLAIR and T2W-TSE regarding white matter (WM)-gray matter (GM). DIR and FLAIR differed signi fi cantly from DIR and T2W-TSE regarding WM-cerebrospinal fl uid (CSF). DIR and FLAIR differed signi fi cantly from DIR and T2W-TSE regarding GM-CSF. Moreover, FLAIR differed signi fi cantly T2W-TSE regarding lesion-WM. DIR and FLAIR, DIR and T2W-TSE, and FLAIR and T2W-TSE differed signi fi cantly regarding lesion-CSF. Conclusion : We can conclude that DIR can add a powerful diagnostic value or act as another option for standardized T2W and FLAIR. Therefore, we intensely recommended adding DIR imaging to imaging protocol of MS.