磁性纳米颗粒

S. Latha, P. Selvamani, S. Palanisamy, Deepak B. Thimiri Govindaraj, Prabha Thangavelu
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引用次数: 0

摘要

磁性纳米粒子是一类可以在外加磁场的帮助下操纵的纳米粒子或纳米材料。这些磁性纳米颗粒构成了镍、钴、铁及其衍生物等材料。这些材料通常直径小于1微米,具有广泛的特性和吸引人的特性,适用于生物医学,如热疗,增强磁共振成像(MRI)数据,补充组织工程工作,改善基于靶标的药物输送和许多其他技术应用。在癌症研究领域,纳米粒子和基于纳米技术的方法和新策略在癌症识别和癌症治疗中的作用迅速增加。氧化铁(Fe3O4, γ-Fe2O3)纳米颗粒(NPs)因其生物相容性、低毒性等优点,广泛应用于药物递送、磁性纳米颗粒增强热疗以及MRI造影剂等领域,是新型生物制药技术的发展方向。
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Magnetic Nanoparticles
The magnetic nanoparticles are said to be a class of nanoparticles or nanomaterials that can be manipulated by the help of externally applied magnetic field. These magnetic nanoparticles constitute materials such as nickel, cobalt, iron, and their derivatives. These are normally smaller than 1 µm in diameter possess wide range of properties and attractive characteristics suitable for biomedical such as used as hyperthermia, enhancing magnetic resonance imaging (MRI) data, supplementing tissue engineering efforts, and improving the target-based drug delivery and many other technological applications. In the field of cancer research, the role of nanoparticles and nanotechnology-based methods and novel strategies have been increasing swiftly for cancer identification and cancer therapy. The iron oxide (Fe3O4, γ-Fe2O3) nanoparticles (NPs) are widely used for the drug delivery, magnetic nanoparticle-enhanced hyperthermia, and also as MRI contrast agents due to its biocompatibility, low toxicity, etc. lead to the growth of novel biopharmaceutical technologies.
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