利用蛋白质本体实现复杂蛋白质组学实验的数据交换

A. Sidhu, T. Dillon, E. Chang
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引用次数: 0

摘要

许多团体正在建立本体论和受控词汇表,以便为日益大规模的实验生物学实验产生的大量混乱数据提供路线图。蛋白质化学领域也不例外,蛋白质本体论(protein ontology, PO)提供了一个框架,在这个框架中,单个分子和复合物可以通过它们的结构、功能和细胞位置来定义,从而引领了该领域。PO使用与所有条目一致的标准命名法在蛋白质数据库中执行搜索。
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Use of Protein Ontology to Enable Data Exchange for Complex Proteomic Experiments
Ontologies and controlled vocabularies are being established by many groups to provide roadmaps through the confused mass of data currently being generated from increasingly large-scale experimental biological experiments. The world of protein chemistry is no exception to this rule, with protein ontology (PO) having lead the field by providing a framework in which individual molecules and complexes can be defined by their structure, function and cellular location. PO performs searches across the protein databases using a standard nomenclature consistent to all entries.
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