J. Babalola, O. Oyelakin, K. Okonjo, K. Brown-Acquaye
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引用次数: 1
摘要
血红蛋白是一种四聚体蛋白，能够分解成二聚体。二聚体又能解离成四聚体。已经发现二聚体比四聚体更活泼。这两种反应性的差异被用来测定兔血红蛋白各种衍生物的四聚体解离常数。该常数在兔血红蛋白的所有衍生物中都是相同的，这意味着结合在血红素上的配体对兔血红蛋白的四聚体-二聚体解离没有显著影响。非洲数学与科学教育研究杂志Vol. 5 2007: pp. 71-76
Determination of the Tetramer-Dimer Equilibrium Constant of Rabbit Hemoglobin
Hemoglobin is a tetrameric protein which is able to dissociate into dimers. The dimers can in turn dissociate into tetramers. It has been found that dimers are more reactive than tetramers. The difference in the reactivity of these two species has been used to determine the tetramerdimer dissociation constant of various derivatives of rabbit hemoglobin. The constant has been found to be the same for all the derivatives of rabbit hemoglobin, implying that the ligand bound on the heme has no significant effect on the tetramer-dimer dissociation of rabbit hemoglobin. African Journal of Educational Studies in Mathematics and Sciences Vol. 5 2007: pp. 71-76
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