个性化医疗的数据表示模型

Hafid Kadi, M. Rebbah, Boudjelal Meftah, O. Lézoray
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引用次数: 1

摘要

个性化医疗利用患者数据,例如,基因组成和关键生物标志物。在数据挖掘过程中,面临的主要挑战是信息丢失、数据类型异构和时间序列表示。针对这些挑战,本文提出了一种新的个性化医疗数据表示模型。建议的模型将考虑结构化、时态和非时态数据及其类型,即数字、标称、日期和布尔类型。在“日期和布尔”数据转换后,对标称数据进行离散处理,同时采用几种聚类技术控制数值数据的分布。最终,转换过程产生三个同构表示,这些表示只有两个维度,以简化对所表示数据集的探索。与符号聚合近似技术相比,该模型保留了时间序列信息,尽可能多地保留了数据,并提供了多种简单的表示方式供探索。
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A Data Representation Model for Personalized Medicine
Personalized medicine exploits the patient data, for example, genetic compositions, and key biomarkers. During the data mining process, the key challenges are the information loss, the data types heterogeneity and the time series representation. In this paper, a novel data representation model for personalized medicine is proposed in light of these challenges. The proposed model will account for the structured, temporal and non-temporal data and their types, namely, numeric, nominal, date, and Boolean. After the "Date and Boolean" data transformation, the nominal data are treated by dispersion while several clustering techniques are deployed to control the numeric data distribution. Ultimately, the transformation process results in three homogeneous representations with these representations having only two dimensions to ease the exploration of the represented dataset. Compared to the Symbolic Aggregate Approximation technique, the proposed model preserves the time-series information, conserves as much data as possible and offers multiple simple representations to be explored.
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