罕见胸壁肿瘤的罕见表现:骨巨细胞瘤

Y. Baiz, O. Afandi, H. Fennane, Y. Msougar
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摘要

巨细胞瘤占所有骨肿瘤的5%。但很少累及前胸壁。临床病例:68岁家庭主妇,因子宫肿瘤行甲状腺切除术11年,现正接受激素替代治疗,子宫切除术6年。她因5个月大的左侧硬乳腺下肿块而就诊,并伴有哺乳动物左侧前胸痛。临床检查发现左乳房下一不规则硬块固定于左第四肋前弓。胸部x线片显示有限的左腋窝及均匀致密影。胸部CT扫描显示以左第四肋骨前弓为中心存在胸壁溶骨性组织密度肿块;在没有使用造影剂的情况下,通过开胸探查发现一个胸壁肿瘤突起,牺牲了第4肢的前弓将相应的肺向内推。手术切除使整个肿瘤在整体上向健康区消融。手术标本的解剖病理学研究显示,形态学和组织病理学方面与伴有巨细胞的肋部肿瘤相符。术后恢复表现为良好的临床和放射学改善。手术后的最后一次检查显示患者仍无症状。临床、生物学和放射学改善良好,下降8个月。结论:巨细胞瘤是侵袭性骨肿瘤,但组织学上是良性的。选择的检查是胸部CT扫描和手术治疗。临床和放射学监测是必要的。复发是罕见的,但它通常需要第二次手术。本临床观察的目的是强调的可能性,虽然罕见,巨细胞肿瘤的情况下,软部分的肿胀,并在肋骨前部的溶解性病变。因此,在这种情况下,必须将该肿瘤添加到诊断列表中。
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Unusual Presentation of a Rare Chest Wall Tumor: Giant Cell Tumor of Bone
Introduction: Giant cell tumours account 5% of all bone tumours. However, the anterior chest wall is rarely involved . Clinical case: This is a 68-year-old housewife who has been thyroidectomized, for 11 years and is under hormone replacement therapy, and hysterectomized for 6 years after a uterine tumor. She is present for the onset of a 5 month old hard submammary mass on the left associated with left anterior chest pain under mammals. The clinical examination had found an irregular hard mass under left mammary which is fixed to the anterior arch of the 4th left rib. A thoracic x-ray showed a limited left hilo-axillary with an homogenously dense opacity. The thoracic CT scan showed the presence of a thoracic parietal mass of osteolytic tissue density centered on the anterior arch of the 4th left rib; without contrast agent, the surgical exploration through thoracotomy revealed a thoracic parietal tumoral process at the expense of the anterior arch of the 4th limb pushing the corresponding lung inwards. Surgical excision allowed ablation of the whole tumor in monobloc towards a healthy zone. The anatomopathological study of the operative specimen showed a morphological and histopathological aspect compatible with a costal tumor with giant cells. The postoperative recovery was marked by a good clinical and radiological improvement. The last check up after the surgery revealed that the patient was still asymptomatic. Good clinical, biological and radiological improvement was noted with a decline of 8 months. Conclusion: Giant cell tumors are aggressive bone tumors, yet histologically benign. The chosen examination is a thoracic CT scan with surgical treatment. A clinical and radiological monitoring is necessary. The recurrence is rare, but it usually necessitates a second surgery. The objective of this clinical observation is to highlight the possibility, although rare, of a giant cell tumor in case of the swelling of the soft parts, and a lytic lesion of the anterior part of a rib. Therefore, this tumor must be added to the list of diagnoses to be mentioned in this situation.
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