角质形成细胞和汗腺细胞亚群细胞核中表皮生长因子受体的免疫组织化学表达。

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247623

C Piérard-Franchimont, A Colige, J Arrese Estrada, C M Lapière, G E Piérard

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引用次数: 16

摘要

我们提出了一种针对170-kD表皮生长因子受体的多克隆抗体。我们发现表皮细胞间的免疫反应性模式，以及角质形成细胞和分泌细胞的细胞质阳性。在一些样本中，在这些类型的细胞中证实了核标记。这些有核标记的细胞和那些在植物血凝素刺激下合成DNA的细胞在地形分布上有密切的相似之处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.

We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of keratinocytes and eccrine secretory cells. In some samples, a nuclear labelling was evidenced in these type of cells. There is a close resemblance in the topographical distribution of these cells with nuclear labelling and those synthesizing DNA under phytohaemagglutinin stimulation.

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Dermatologica

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