{"title":"Ebstein异常，可能与药物病因有关?病例报告","authors":"B. Animasahun, O. A. Ajayi, F. O. Lawani, E. Disu","doi":"10.17140/hroj-8-158","DOIUrl":null,"url":null,"abstract":"Ebstein’s anomaly is a congenital malformation of the heart that is characterized by downward displacement of an abnormal tricuspid valve into the right ventricle. It is rare, with an incidence of 1 in 200,000 live births. Etiology is unknown. Our patient was exposed to artemether-lumefantrine, ciprofloxacin, and ibuprofen (not previously linked with Ebstein’s anomaly) at about four weeks of gestation. An obstetric scan at 33 weeks’ gestation, was the first clue to the diagnosis.","PeriodicalId":114945,"journal":{"name":"Heart Research – Open Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case Report\",\"authors\":\"B. Animasahun, O. A. Ajayi, F. O. Lawani, E. Disu\",\"doi\":\"10.17140/hroj-8-158\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ebstein’s anomaly is a congenital malformation of the heart that is characterized by downward displacement of an abnormal tricuspid valve into the right ventricle. It is rare, with an incidence of 1 in 200,000 live births. Etiology is unknown. Our patient was exposed to artemether-lumefantrine, ciprofloxacin, and ibuprofen (not previously linked with Ebstein’s anomaly) at about four weeks of gestation. An obstetric scan at 33 weeks’ gestation, was the first clue to the diagnosis.\",\"PeriodicalId\":114945,\"journal\":{\"name\":\"Heart Research – Open Journal\",\"volume\":\"42 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Heart Research – Open Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17140/hroj-8-158\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart Research – Open Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17140/hroj-8-158","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case Report
Ebstein’s anomaly is a congenital malformation of the heart that is characterized by downward displacement of an abnormal tricuspid valve into the right ventricle. It is rare, with an incidence of 1 in 200,000 live births. Etiology is unknown. Our patient was exposed to artemether-lumefantrine, ciprofloxacin, and ibuprofen (not previously linked with Ebstein’s anomaly) at about four weeks of gestation. An obstetric scan at 33 weeks’ gestation, was the first clue to the diagnosis.
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