神经母细胞瘤磁共振成像、间碘苄基胍显像和骨髓组织学/细胞学的前瞻性比较

European Journal of Cancer and Clinical Oncology Pub Date : 1991-12-01 DOI:10.1016/0277-5379(91)90415-A

Robin Corbett , Julie Olliff , Neil Fairley , Judy Moyes , Janet Husband , Ross Pinkerton , Richard Carter , Jennifer Treleaven , Timothy McElwain , Simon Meller

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引用次数: 39

摘要

通过对磁共振成像(MRI)、123I间碘苄基胍(mIBG)显像和髂后嵴骨髓穿刺和环肺活检在30次评估(19例)中的前瞻性比较，16次评估(53.3%)显示三种技术之间的一致性。10例(33.3%)MRI和mIBG显示骨髓活检未发现的异常。MRI是4项评估中唯一显示骨髓异常的技术(13.3%)。此外，MRI在16个平行评估中显示更多的异常部位。我们的结论是，MRI作为一种非侵入性的检测神经母细胞瘤骨髓浸润的方法是有希望的，但需要进一步评估MRI在这种情况下的特异性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A prospective comparison between magnetic resonance imaging, meta-iodobenzylguanidine scintigraphy and marrow histology/cytology in neuroblastoma

A prospective comparison between magnetic resonance imaging (MRI), ¹²³I meta-iodobenzylguanidine (mIBG) scintigraphy and posterior iliac crest marrow aspiration and trephine biopsy in 30 assessments (19 patients) showed concordance between the three techniques in 16 assessments (53.3%). In 10 (33.3%), MRI and mIBG revealed abnormalities not detected by marrow biopsy. MRI was the only technique to demonstrate marrow abnormality in four assessments (13.3%). In addition, MRI revealed more sites of abnormality in 16 parallel assessments. We conclude that MRI shows promise as a non-invasive means of detecting bone marrow infiltration by neuroblastoma, but that further evaluation of the specificity of MRI in this setting is indicated.

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