产前晚期胎儿或新生儿死亡的预期和围产期团队方法

M. Krekora, M. Grzesiak, M. Słodki, E. Gulczyńska, I. Maroszyńska, M. Respondek-Liberska, F. Chervenak, L. Mccullough
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引用次数: 1

摘要

摘要简介:本研究的目的是介绍我们目前在妊娠晚期对最严重先天性畸形患者和家庭进行咨询的做法,并为我们的团队和相关的医疗保健/社会保健专业人员制定实用指南。材料与方法:回顾性分析2017年来自单一三级中心的一系列胎儿病例。产科病史,产前发现异常的时间(妊娠1、2或3个月),最后一次胎儿超声心动图检查到分娩的时间,分娩类型,新生儿出生体重和新生儿死亡时间。整个研究组分为早亡(分娩后第1天)和晚亡(分娩后第1天)。结果:产妇平均年龄为30岁、4 +/- 5岁、6岁,变化范围为26 ~ 38岁。既往无母体慢性疾病,既往患儿无先天性畸形。所有女性在妊娠早期均行超声检查,9例显示正常(NT测量值< 2mm), 2例发现心外异常:膈疝和脐膨出(两胎核型均为46,XY)。其中9例在妊娠中期发现异常,产妇希望继续妊娠。有8例新生儿在分娩后60分钟内死亡,包括1例产时死亡和3例重症监护病房“晚期”新生儿死亡(第12、21和22天)。我们强调产前团队的方法和咨询未来的父母,以准备他们的新生儿结局差。结论:1。在最严重的情况下,当怀疑胎儿或新生儿死亡时,两种不同的专家意见可能是不够的,在最终决定之前应该推荐第三种意见。2. 在预期胎儿/新生儿死亡的情况下,一个胎儿专家小组是必要的,以便为涉及这一难题的各方准备一份建议围产期管理的书面报告。
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Prenatal 3RD Trimester Expectation of Fetal or Neonatal Demise and Perinatal Team Approach
Abstract INTRODUCTION: The aim of this study was to present our current practice of counseling patients and families with the most severe congenital malformations in the 3rd trimester of pregnancy and to develop practical guidelines for our team and involved healthcare/ socialcare professionals. MATERIAL & METHODS: It was a retrospective evaluation of a series of fetal cases in 2017 from single tertiary center. Maternal obstetrical medical history, time of prenatal detection of the anomaly (1st, 2nd or 3rd trimester), time between last fetal echocardiography and delivery, type of delivery, neonatal birth weight and time of neonatal demise. The total study group was subdived into early demise (during the 1st day after delivery) or late demise > 1st day after delivery. RESULTS: Mean maternal age was 30,4 +/- 5,6 years, and varied between 26 and 38 years. No chronic maternal diseases were found in medical history and no congenital malformations were present in previous children. All women had 1st trimester ultrasound, in 9 cases, it was reported as normal (with NT measurement < 2 mm), in 2 cases extracardiac abnormalities were detected: diaphragmatic hernia and omphalocele ( in both fetal karyotype 46,XY). In nine cases, the abnormalities were detected in midgestation and with maternal wish to continue the pregnancies. There were 8 neonatal deaths within 60 minutes after delivery, including one intrapartum death and 3 “late” neonatal deaths in the intensive care unit (on 12th, 21st and 22nd day). We stress upon the prenatal team approach and counseling of future parents, in order to prepare them for poor neonatal outcome. CONCLUSIONS: 1. In the most severe cases when fetal or neonatal demise was suspected, the two different opinions of specialists might not be enough and a third opinion should be recommended before final decision. 2. A Fetal Team of specialists is necessary in cases of expected fetal/neonatal demise in order to prepare a written report of recommended perinatal management for all sides involved in this difficult problem.
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