造血干细胞移植

Paediatric Haemotology and Oncology Pub Date : 2022-01-01 DOI:10.1093/med/9780198779186.003.0015

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引用次数: 0

摘要

造血干细胞移植(HSCT)用于治疗多种血液病和某些实体恶性肿瘤，以及其他几种严重的血液病、免疫学、自身免疫性和代谢性疾病。本章描述了HSCT的目的、原则和适应症。概述了HSCT的受体和供体准备，以及包括移植物抗宿主病(GvHD)预防在内的受体调节治疗。描述了造血干细胞移植的急性和晚期并发症，包括移植物抗宿主病。

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Haemopoietic stem cell transplantation

Haemopoietic stem cell transplantation (HSCT) is used to treat a wide variety of haematological and certain solid malignancies, as well as several other serious haematological, immunological, auto-immune and metabolic diseases. This chapter describes the aims and principals of, and indications for, HSCT. The recipient and donor preparation for HSCT, and recipient conditioning treatment including graft-versus-host disease (GvHD) prophylaxis, are outlined. The acute and late complications of HSCT, including GvHD, are described.

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