{"title":"1974","authors":"D. Gifford","doi":"10.4324/9781315825151-80","DOIUrl":null,"url":null,"abstract":"carcinoma, and it would appear that this tumour is a highly malignant variant of the bronchial carcinoid.6 Less common are the adenoid cystic carcinoma and the mucoepidermoid carcinoma, tumours noted most often in the salivary glands. The adenoid cystic carcinoma, also called the cylindroma, consists of trabeculae, columns, and cords of epithelial cells, some enclosing cystic spaces, which are surrounded by a dense, hyaline stroma. The mucoepidermoid carcinoma contains a mixture of squamous-cell and mucus-secreting glandular elements. A true mucus-4secreting adenoma has also been described, but it is very rare.7 Recently A. D. Turnibull and his colleagues have reviewed 61 cases of bronchial adenoma which had occurred over a period of 43 years.8 These comprised 44 carcinoid tumours, 12 mucoepidermoid carcinomata, and 5 adenoid cystic carcinomata. Most of these tumours occurred in patients between the ages of 40 and 70 years, and while the sex incidence was equal in the carcinoid group there was a male predominance in the other two groups of tumours. None of the cases of carcinoid tumour showed the typical endocrine syndrome. The most conspicuous finding in this series was the high degree of malignancy of the tumours. Only 59W/', of the patients with carcinoid tumour and 600,W of those with adenoid cystic carcinoma survived for five years, while all those with mucoepidermoid carcinoma had died during that period of time. This is especially surprising, as mucoepidermoid carcinoma is usually regarded as the most benign type of bronchial adenoma,7 other than the rare mucus-secreting adenoma, which was not encountered in this series. The observations of Turnbull and his colleagues once again contradict the traditional teaching that the various types of bronchial adenoma behave in a benign fashion and are usually compatible with prolonged survival. The time has surely come to expunge the term bronchial adenoma, and to group the tumours that have been included under this heading as bronchial carcinoids, mucoepidermoid carcinomata, and adenoid cystic carcinomata. While they are certainly less malignant than the usual varieties of lung cancer-the oat-cell carcinoma, adenocarcinoma, and squamous-cell carcinoma-their serious nature must be fully acknowledged.","PeriodicalId":344571,"journal":{"name":"Literatur in der SBZ/DDR","volume":"108 4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1974-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"1974\",\"authors\":\"D. Gifford\",\"doi\":\"10.4324/9781315825151-80\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"carcinoma, and it would appear that this tumour is a highly malignant variant of the bronchial carcinoid.6 Less common are the adenoid cystic carcinoma and the mucoepidermoid carcinoma, tumours noted most often in the salivary glands. The adenoid cystic carcinoma, also called the cylindroma, consists of trabeculae, columns, and cords of epithelial cells, some enclosing cystic spaces, which are surrounded by a dense, hyaline stroma. The mucoepidermoid carcinoma contains a mixture of squamous-cell and mucus-secreting glandular elements. A true mucus-4secreting adenoma has also been described, but it is very rare.7 Recently A. D. Turnibull and his colleagues have reviewed 61 cases of bronchial adenoma which had occurred over a period of 43 years.8 These comprised 44 carcinoid tumours, 12 mucoepidermoid carcinomata, and 5 adenoid cystic carcinomata. Most of these tumours occurred in patients between the ages of 40 and 70 years, and while the sex incidence was equal in the carcinoid group there was a male predominance in the other two groups of tumours. None of the cases of carcinoid tumour showed the typical endocrine syndrome. The most conspicuous finding in this series was the high degree of malignancy of the tumours. Only 59W/', of the patients with carcinoid tumour and 600,W of those with adenoid cystic carcinoma survived for five years, while all those with mucoepidermoid carcinoma had died during that period of time. This is especially surprising, as mucoepidermoid carcinoma is usually regarded as the most benign type of bronchial adenoma,7 other than the rare mucus-secreting adenoma, which was not encountered in this series. The observations of Turnbull and his colleagues once again contradict the traditional teaching that the various types of bronchial adenoma behave in a benign fashion and are usually compatible with prolonged survival. The time has surely come to expunge the term bronchial adenoma, and to group the tumours that have been included under this heading as bronchial carcinoids, mucoepidermoid carcinomata, and adenoid cystic carcinomata. While they are certainly less malignant than the usual varieties of lung cancer-the oat-cell carcinoma, adenocarcinoma, and squamous-cell carcinoma-their serious nature must be fully acknowledged.\",\"PeriodicalId\":344571,\"journal\":{\"name\":\"Literatur in der SBZ/DDR\",\"volume\":\"108 4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1974-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Literatur in der SBZ/DDR\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4324/9781315825151-80\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Literatur in der SBZ/DDR","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4324/9781315825151-80","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
癌,看来这个肿瘤是支气管类癌的高度恶性变异不太常见的是腺样囊性癌和粘液表皮样癌,这些肿瘤最常见于唾液腺。腺样囊性癌,也称为柱状癌,由上皮细胞小梁、柱状和索状组成,一些上皮细胞包围着囊性间隙,囊性间隙被致密的透明间质包围。黏液表皮样癌包含鳞状细胞和分泌黏液的腺体成分。真正的粘液分泌腺瘤也有报道,但非常罕见最近,a . D. Turnibull和他的同事回顾了43年来发生的61例支气管腺瘤其中类癌44例,粘液表皮样癌12例,腺样囊性癌5例。这些肿瘤大多发生在40至70岁之间的患者中,虽然类癌组的性别发病率相等,但其他两组肿瘤中男性占主导地位。类癌无典型内分泌综合征。在这个系列中最显著的发现是肿瘤的高度恶性。类癌患者和腺样囊性癌患者的5年生存率分别为59W/ s和600w / s,而粘液表皮样癌患者在5年内全部死亡。这是特别令人惊讶的,因为粘液表皮样癌通常被认为是支气管腺瘤中最良性的类型,7除了罕见的粘液分泌腺瘤,这在本系列中没有遇到。特恩布尔和他的同事们的观察结果再次反驳了传统的观点,即各种类型的支气管腺瘤表现为良性,通常可以延长生存时间。现在是时候把支气管腺瘤这个术语去掉了,并把包括在这个标题下的肿瘤归为支气管类癌、粘液表皮样癌和腺样囊性癌。虽然它们的恶性程度肯定不如常见的肺癌——燕麦细胞癌、腺癌和鳞状细胞癌——但它们的严重性必须得到充分认识。
carcinoma, and it would appear that this tumour is a highly malignant variant of the bronchial carcinoid.6 Less common are the adenoid cystic carcinoma and the mucoepidermoid carcinoma, tumours noted most often in the salivary glands. The adenoid cystic carcinoma, also called the cylindroma, consists of trabeculae, columns, and cords of epithelial cells, some enclosing cystic spaces, which are surrounded by a dense, hyaline stroma. The mucoepidermoid carcinoma contains a mixture of squamous-cell and mucus-secreting glandular elements. A true mucus-4secreting adenoma has also been described, but it is very rare.7 Recently A. D. Turnibull and his colleagues have reviewed 61 cases of bronchial adenoma which had occurred over a period of 43 years.8 These comprised 44 carcinoid tumours, 12 mucoepidermoid carcinomata, and 5 adenoid cystic carcinomata. Most of these tumours occurred in patients between the ages of 40 and 70 years, and while the sex incidence was equal in the carcinoid group there was a male predominance in the other two groups of tumours. None of the cases of carcinoid tumour showed the typical endocrine syndrome. The most conspicuous finding in this series was the high degree of malignancy of the tumours. Only 59W/', of the patients with carcinoid tumour and 600,W of those with adenoid cystic carcinoma survived for five years, while all those with mucoepidermoid carcinoma had died during that period of time. This is especially surprising, as mucoepidermoid carcinoma is usually regarded as the most benign type of bronchial adenoma,7 other than the rare mucus-secreting adenoma, which was not encountered in this series. The observations of Turnbull and his colleagues once again contradict the traditional teaching that the various types of bronchial adenoma behave in a benign fashion and are usually compatible with prolonged survival. The time has surely come to expunge the term bronchial adenoma, and to group the tumours that have been included under this heading as bronchial carcinoids, mucoepidermoid carcinomata, and adenoid cystic carcinomata. While they are certainly less malignant than the usual varieties of lung cancer-the oat-cell carcinoma, adenocarcinoma, and squamous-cell carcinoma-their serious nature must be fully acknowledged.