急性冠脉综合征患者经皮冠状动脉介入治疗的性别差异分析

H. Tareen, A. Sher, Fouzia Goher, I. Hussain, Mohsin Saif, M. R. Khan
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引用次数: 0

摘要

背景:目前关于诊断为急性冠脉综合征(ACS)患者的预后的知识有限。关于干预后结果的性别差异和管理差异的数据不足。目的:本研究旨在确定ACS患者的性别相关差异。这项研究还旨在确定这些差异是如何在一年的时间跨度内消失的。研究设计:采用统计学方法进行回顾性研究。材料与方法:收集在拉瓦尔品第AFIC就诊的1000例患者的资料。研究时间为6个月,从2021年8月到2022年1月。选择诊断为非st段抬高急性冠状动脉综合征的患者。医院的伦理和审查委员会批准了这项研究。进一步将患者分为ACS I型和ACS II型。结果:在1000例患者中,急性冠状动脉综合征I型650例,急性冠状动脉综合征II型350例。650例ACSI患者中,男性430例,女性220例。在350名ACSII中,有230名男性和120名女性。研究表明,老年妇女有较高的心衰和高血压病史。在女性中也观察到较高的死亡率。住院冠状动脉造影与女性性别的相关性很弱。医生低估了与确诊患者相关的风险,导致在治疗中较少使用侵入性策略。结论:由于对ACS患者相关风险的低估,对ACS患者的治疗应采用保守方法。住院预后差与女性有关。研究发现,与男性患者相比,女性接受冠状动脉成形术和其他心脏手术的可能性较小。男性和女性都需要意识到要消除这种性别差异。关键词:冠状动脉造影,急性冠状动脉综合征,经皮冠状动脉介入治疗,介入后结果和心力衰竭。
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The Insight into the Sex Differences in the Patients Diagnosed with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention
Background: The limited knowledge is present about the outcomes associated with the patients diagnosed with acute coronary syndrome (ACS). The insufficient data about the sex difference in the post-interventions outcomes and disparities in management is available. Objective: This study aim was to determine the sex-related differences in the patient diagnosed with ACS. This study also aimed to determine how these differences have perished in a time span of one year. Study design: It is a retrospective study with the statistical approaches. Material and Methods: The data of the 1000 patients that visited to AFIC Rawalpindi was collected. The duration of the study was 6 months, from August 2021 to January 2022. The patients were diagnosed with the non-ST-segment elevation acute coronary syndrome were selected. The ethical and review board committee of the hospital approved the study. The patients were further grouped to ACS I and ACS II. Results: Out of the 1000 patients taken, there were 650 patients that had acute coronary syndrome I while there were 350 patients that had acute coronary syndrome II. Among the 650 patients of ACSI there were 430 males and 220 were female patients. And among the 350 ACSII there were 230 males and 120 were female. The study indicate that the older women have the higher cases with reported history of heart failure and hypertension. The higher mortality cases were also observed in the females. The association between coronary angiography in-hospital use and female gender was very weak. The physicians underestimate the risk associated with the diagnosed patients that leads to less use of invasive strategies for treatment of the men and women. Conclusion: Due to underestimation of the risks associated with the ACS patients the conservative methods are used for the treatment of the women. The poor in-hospital outcome are associated with the female gender. It was found that women are less likely to undergo coronary artery angioplasty and other cardiac procedures as compared to the male patients. Awareness is needed for both male and female to eliminate this gender disparity. Keywords: Coronary angiography, acute coronary syndrome, percutaneous coronary intervention, post-interventions outcomes and heart failure.
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