乙肝病毒携带者母亲所生新生儿接种乙肝疫苗后的免疫保护时间

Microbiologica Pub Date : 1991-07-01

C Belloni, P Orsolini, L Soldini, D Campisi, A Chiesa, R Ciceri, G Filice

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引用次数: 0

摘要

一组43名hbsag阳性母亲所生的健康新生儿在接受乙型肝炎血浆源性疫苗和乙型肝炎高免疫球蛋白治疗后，评估其保护性HBsAb滴度的存在。在36个月大时，我们发现有相当数量的儿童HBsAb血清水平较低。这表明有必要进行密切的血清学随访，以评估接种疫苗加强剂的最佳时机。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Duration of immune protection after hepatitis B vaccine in newborns from HBsAg-positive carrier mothers.

A group of 43 healthy neonates born from HBsAg-positive mothers were evaluated for the presence of protective HBsAb titre after administration of hepatitis B plasma-derived vaccine and hepatitis B hyperimmune-globulin. At 36 months of life we found that a significant number of children had a low HBsAb serum level. This suggests that a close serologic follow-up is necessary to evaluate the optimal timing for the administration of a booster dose of the vaccine.

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来源期刊

Microbiologica

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